Heterocyclic amines are formed during high temperature cooking of foods such as meat and fish. Although heterocyclic amines are known mutagens and some of them are shown to be carcinogenic to experimental animals, the carcinogenic potential of heterocyclic amines in humans has yet to be established. The most important criteria in determining the relationship between heterocyclic amines and huma...

Work-related musculoskeletal disorders (WMSDs) are debilitating for workers and costly for employers. Existing exposure assessment tools were modified for rapid job physical exposure and company organizational exposure assessment. These were augmented with injured worker interviews to "put the meet on the bones" in characterizing risk. These risk assessments are conducted in all industry sectors.

This paper describes a new method (DREAM) for structured, semi-quantitative dermal exposure assessment for chemical or biological agents that can be used in occupational hygiene or epidemiology. It is anticipated that DREAM could serve as an initial assessment of dermal exposure, amongst others, resulting in a ranking of tasks and subsequently jobs. DREAM consists of an inventory and evaluation...

Over the past three decades, a formal risk assessment process has been developed to provide consistent and transparent methods for the assessment of potential human health risks from exposure to environmental chemicals. Given a focus on risk to human health, epidemiological studies that identify associations between exposure to environmental chemicals and adverse health effects in humans have t...

BACKGROUND AND OBJECTIVES In many places in Europe, the ambient air pollution exceeds the levels considered to be safe for health. The objective of the paper is to review and summarise the methods of assessment of its impact on health, and to indicate the contributions of various research disciplines, particularly environmental epidemiology. METHODS The framework for assessment of impact is b...

background: the aim of this paper was the comparison of ergonomic risk assessment results (final score and action levels) for the entire body as determined using quick exposure check (qec) and rapid entire body assessment (reba).  materials and methods: this was a cross-sectional study in which all 82 workers engaged in various processes with different activities in an anodizing and aluminum pr...

A method is proposed for integrated probabilistic risk assessment where exposure assessment and hazard characterization are both included in a probabilistic way. The aim is to specify the probability that a random individual from a defined (sub)population will have an exposure high enough to cause a particular health effect of a predefined magnitude, the critical effect size (CES). The exposure...

background: prolonged inhibition of acetylcholine esterase may lead to the intermediate syndrome. neuromuscular junction (nmj) dysfunction has been shown with repetitive nerve stimulation (rns). subclinical nmj dysfunction may also occur. we aimed to examine the nmj function following acute organophosphorus (op) poisoning by using exercise modified slow rns. methods: a cohort study was conducte...