PURPOSE/OBJECTIVES To describe the Heiney-Adams Recruitment Framework (H-ARF); to delineate a recruitment plan for a randomized, behavioral trial (RBT) based on H-ARF; and to provide evaluation data on its implementation. DATA SOURCES All data for this investigation originated from a recruitment database created for an RBT designed to test the effectiveness of a therapeutic group convened via...

Clinical trial allocation in multinational pharmaceutical companies includes country selection and site selection. With emphasis on site selection, the overall aim of this study was to examine which factors pharmaceutical companies value most when allocating clinical trials. The specific aims were (1) to identify key decision makers during country and site selection, respectively, (2) to evalua...

T his issue of the Tobacco Control contains an account by Professor Eiji Yano complementing an earlier report about the disturbing circumstances of his association in the early 1990s with tobacco industry lawyers Covington and Burling—specifically, with the company’s then employee Christopher Proctor, now head of science and regulation at British American Tobacco (BAT). Dr Proctor and Mr Peter ...

We tested changes in cortical functional response to auditory patterns in a configural learning paradigm. We trained 10 human listeners to discriminate micromelodies (consisting of smaller pitch intervals than normally used in Western music) and measured covariation in blood oxygenation signal to increasing pitch interval size in order to dissociate global changes in activity from those specifi...

Although research has identified age-related changes in neural recruitment during emotional memory encoding, it is unclear whether these differences extend to retrieval. In this study, participants engaged in a recognition task during a functional magnetic resonance imaging scan. They viewed neutral titles and indicated whether each title had been presented with an image during the study phase....

A bewildering array of proteins containing the caspase recruitment domain (CARD) have now been identified. Previously, CARD-CARD interactions have been shown to be involved in the assembly of protein complexes that promote caspase processing and activation in the context of apoptosis. However, as the family of CARD-containing proteins has grown, it has become apparent that the majority of these...

There are substantial declines in behavioral measures of cognitive function with age, including decreased function of executive processes and long-term memory. There is also evidence that, with age, there is a decrease in brain volume, particularly in the frontal cortex. When young and older adults perform cognitive tasks that depend heavily on frontal function, neuroimaging evidence indicates ...

Aims Understanding the processes driving forest dynamics requires considering that species within communities do not respond in a coordinated manner to external factors. We argue temporal turnover composition results from contrasting differences life-history and functional strategies (demography seed wood traits) might simultaneously promote stability dynamism by operating on distinct subsets o...

The purpose of this study is to find out and analyze the process investigating criminal acts fraud in recruitment civil servants at Pacitan Police Resort. To factors causing occurrence against acceptance Candidates for Civil Servants Resort Police. This used an empirical juridical approach, with descriptive analysis research specifications. data was secondary data. method collection obtained fr...

The findings on the strategies employed by endophytic microbes have provided salient information to researchers need maximally explore them as bio-input in agricultural biotechnology. Biotic and abiotic factors are known influence microbial recruitments from external plant environments into tissues. Endophytic exhibit mutualism or antagonism association with host plants. beneficial types contri...