BACKGROUND Diagnosis of pulmonary (PTB) and extra-pulmonary tuberculosis (EPTB) in smear-negative patients can be difficult. We assessed retrospectively the performance of Xpert MTB/RIF system (Xpert, Cepheid) in diagnosing smear-negative tuberculosis (TB), which represents the most common form of TB in a low incidence setting. METHODS Performance of Xpert was compared to acid-fast microscopi...

BACKGROUND Lipid peroxidation, nitric oxide, carbonyl protein, causing production of reactive oxygen and reactive nitrogen intermediates that lead to oxidative, nitrosative stress. The stress is found to cause deterioration in the cellular function, mutagenesis, and DNA damage. The oxidative stress is correlated with the antioxidant vitamins status. METHODS Newly diagnosed cultured positive s...

background: to determine the mean and median delays in pulmonary tuberculosis (ptb) diagnosis among adults in one of the world’s highest gross domestic product per capita countries and identify patient and health system‑related reasons for these delays. methods: this is a cross‑sectional, face‑to‑face, prospective study of 100 subjects with confirmed ptb, conducted at main tuberculosis (tb) adm...

the purpose of this study was to evaluate the characteristics of anthracofibrosis and the relationship between bronchial anthracofibrosis (baf) and tuberculosis during autopsy in the iranian legal medicine organization (lmo). in this cross-sectional study, 385 subjects who had died from 2007 to 2010 were examined. a questionnaire having information such as the deceased's age, sex, ethnicity, sm...

introduction: about one third of the world's population is infected with tuberculosis (tb) and each year, about 1.5 to 2 million people die from tb. procalcitonin (pct) is an inflammatory marker that its level has variable materials and methods: this conducted on patients with pulmonary tb. data were collected using a check list. the serum level of pct was measured by elisa test at the beg...

UNLABELLED Bone and joint tuberculosis is a chronic debilitating condition that leads to progressive damage and even deformity of joints. It may affect one or multiple sites. It could present in a myriad of ways which may result in an incorrect diagnosis being made. Common misdiagnoses include seronegative inflammatory arthritis, septic arthritis, malignancy, osteoporotic fractures and mechanic...

Amyloidosis is defined as the presence of extra-cellular deposits of an insoluble fibrillar protein, amyloid. The pulmonary involvement of amyloidosis is usually classified as tracheobronchial, parenchymal nodular, or diffuse alveolar septal. A single nodular lesion can mimic various conditions, including malignancy, pulmonary tuberculosis, and fungal infection. To date, only one case of nodula...

BACKGROUND Although infectious diseases are the most common sources for the fever of unknown origin (FUO), but the spectrum of infectious diseases is changing overtime. The purpose of the study was to define the clinical spectrum and changing the pattern of FUO. METHODS This existing data based study was undertaken from 2007 to 2011. One hundred-six patients fulfilling the modified criteria f...

Musculoskeletal tuberculosis accounts for 1-2% of all types of tuberculosis. Tubercular abscess of the chest wall accounts for 1-5% of all cases of musculoskeletal tuberculosis. Herein, we report a case of tubercular abscess of the chest wall. The occurrence of caries rib and cold abscess of the chest wall with concomitant pulmonary tuberculosis, and tubercular lympha-denitis of neck and medias...

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