Matrix metalloproteinases are an integral component of the organ-specific tissue microenvironment, primarily participating in regulation state integrative-buffer metabolic environment, remodeling, morphogenesis and immunogenesis, genesis pathological vascular diseases. Therefore, issues related to matrix metalloproteinase activity under altered gravity a matter high urgency for space biomedicin...

Growth and ovulation of follicles, and development, maintenance, and regression of the corpus luteum depend on cyclical remodelling of the extracellular matrix. The extracellular matrix consists of proteinaceous and non-proteinaceous components and provides the tissue-specific, extracellular architecture to which cells attach, and modulates the activities of cells through cell surface receptors...

Cells adhere to the extracellular matrix through interaction with adhesive extracellular matrix glycoproteins, including fibronectin, laminins, vitronectin, thrombospondins, tenascins, entactins (or nidogens), nephronectin, fibrinogen, and others. Most adhesive glycoproteins bind cells through cell surface integrin receptors in conjunction with other cell surface receptors, such as dystroglycan...

Testosterone is believed to play a significant role in spermatogenesis, but its contribution to the process of spermatogenesis is not completely understood. Given that extracellular matrix (ECM) facilitates differentiation of spermatogonial stem cells (SSCs) during culture, the present study was conducted to elucidate whether testosterone contribute to the permissive effect of ECM on SSCs diffe...

introduction perforation of maxillary sinus mucous membrane is of the most prevalent complication during open sinus lift surgery. moreover, such complication can usually be managed by an absorbable membrane. as far as absorbable membranes are concerned, decellularized maxillary sinus mucous membranes, which is an extracellular matrix, can be used as a biologic scaffold and insulating membrane i...

Cellulose-based wound dressings are increasingly in demand due to their biocompatibility and extracellular matrix (ECM) mimicking properties.