Among the clinical presentation of plasma cell proliferative disorders the extramedullary plasmacytomas are the most infrequent after multiple myeloma and plasma cell tumours of the bones. The plasmacytoma of the thyroid gland to our knowledge has never been reported from Pakistan so far. We present the clinical picture and clinical challenges posed in diagnosis and treatment by this unusual pr...

Renal solitary extramedullary plasmacytomas belong to a group of plasma cell neoplasms, which generally have been associated with renal cell carcinoma. We present a case report of a patient with collision tumor histology of extramedullary plasmacytoma and clear cell renal cell carcinoma, the first in the known literature. Standard work-up for a plasma cell neoplasm was conducted and the mass wa...

Multiple myeloma is a neoplastic disorder caused by the proliferation of a transformed B lymphoid progenitor cell that gives rise to a clone of immunoglobulin-secreting cells. Other plasma cell tumours include solitary plasmacytoma of bone (SPB) and extramedullary plasmacytomas (EMP). Despite an apparent common origin there exist pathological and clinical differences between these neoplasms and...

Extramedullary plasmacytoma (EMP) is a rare monoclonal plasmacytic proliferation involving upper airways in 80% of cases. The heterogeneous pattern of frequency in the head and neck area may result in insidious clinical expressions that are potentially lethal for the patient. The presentation and management of two suggestive clinical photographs characterized by sudden and aggressive EMP develo...

PURPOSE The aim of this study is to determine the diagnostic and prognostic role of baseline spinal magnetic resonance imaging (MRI) in patients with multiple myeloma. MATERIALS AND METHODS We enrolled patients newly diagnosed with multiple myeloma from 2004-2011 at a single center. Abnormal MRI findings that were not detected in radiographs have been analyzed and categorized as malignant com...

Multiple myeloma is a plasma cell tumor that homes to and expands in the bone marrow and that, despite the new available drugs, remains incurable. Extramedullary plasmacytoma is a not frequent manifestation during the natural history of multiple myeloma and is frequently associated with plasma cell bone marrow infiltration. The most common locations for an EMP include the gastrointestinal tract...

Plasmacytomas are monoclonal plasma cells proliferations originating either in localized osseous tissue or in soft tissue (extramedullary plasmacytoma, EMP). Although many such lesions are found in the bone marrow, fewer arise in extramedullary tissue. A solitary EMP involving the adrenal gland is extremely rare, with only 7 cases having been reported in the literature thus far. Here, we descri...