In this paper, a method by which the fluid velocity profile and the net flow rate in self-wiping co-rotating twin screw extruders can be estimated without determining the pressure gradient has been proposed. The method involves using analytical technique to determine the fluid velocity in the local zones of the extruder such as the down channel and axial velocity and subsequently, the net flow ...

The aim of this study was to evaluate hot-melt extrusion (HME) as a continuous process to form cyclodextrin (CD) inclusion complexes in order to increase the solubility and dissolution rate of itraconazole (ITZ), a class II model drug molecule of the Biopharmaceutics Classification System. Different CD derivatives were tested in a 1:1 (CD:ITZ) molar ratio to obtain CD ternary inclusion complexe...

Outbreaks of salmonellosis and recalls of low-moisture foods including extruded products highlight the need for the food and feed industries to validate their extrusion processes to ensure the destruction of pathogenic microorganisms. Response surface methodology was employed to study the effect of moisture and temperature on inactivation by extrusion of Enterococcus faecium NRRL B-2354 in a c...

An initial study of 3d printing with compound filament using different plastic matrices and sugar cane bagasse as the filler was conducted. In order to do this, a reverse engineering process was made to several 3d printer extruders to determine how to change the extruder in order to be able to print with the filament. To obtain the filament, a plastic extruder was modified to obtain a compound ...