This work first considers a review of the dominant current methods for fibre Bragg grating wavelength interrogation. These methods include WDM interferometry, tunable filter (both Fabry-Perot and acousto-optic) demultiplexing, CCD/prism technique and a newer hybrid method utilizing Fabry-Perot and interferometric techniques. Two applications using these techniques are described: hull loads moni...

Narrow-band emission of spectral width down to ~0.05 nm line-width is achieved in the random distributed feedback fiber laser employing narrow-band fiber Bragg grating or fiber Fabry-Perot interferometer filters. The observed line-width is ~10 times less than line-width of other demonstrated up to date random distributed feedback fiber lasers. The random DFB laser with Fabry-Perot interferomete...

We demonstrate a method to manage the locked multichannel output from a mode-locked Cr:forsterite laser cavity, which was achieved by inserting a Fabry–Perot etalon into the oscillator. It is found that the thickness of the etalon determines the channel spacing and its surface reflectivity affects channel linewidth and channel pulsewidth. Following Fabry–Perot theory, we can use these facts to ...

The influence of temperature on coated (2%) and uncoated Fabry-Pérot laser output in a proposed colorless WDM system with self-seeding via modulation averaging reflector is studied. In particular, the connection between the information about the optical laser output from the laser integrated monitor photodetector and optical power output of the entire system with temperature change of the laser...

We experimentally demonstrate the phase relations of 3-port gratings by investigating 3-port coupled Fabry-Perot cavities. Two different gratings which have the same 1st order diffraction efficiency but differ substantially in their 2nd order diffraction efficiency have been designed and manufactured. Using the gratings as couplers to Fabry-Perot cavities we could validate the results of an ear...

Fabry disease (FD) is an X-linked lysosomal storage disorder that affects both men and women. The manifestations of this heterogeneous disease are multisystemic and progressive. Prior to the development of enzyme replacement therapy, the management and treatment for Fabry disease was largely nonspecific and supportive. Because enzyme replacement therapy became commercially available in 2001, a ...

The noise and performance limitations of optical sensors that utilize Fabry–Perot interferometry detection are investigated. A Fabry–Perot interferometer consists of two partially transparent parallel plates with reflective inner surfaces. The plates form a cavity with an optical resonance that depends on the distance between them. At resonant wavelengths, the incident light energy is transmitt...

2014 Enzyme replacement therapies substitute particular enzymes in individuals who have deficient or absent levels of enzymatic activity due to inherited defects. Fabry disease, a rare X-linked genetic disorder yet common lysosomal storage disease, is due to the impaired activity of alpha-galactosidase A. Currently, there are two enzyme preparations available for the treatment of Fabry disease:...

The use of personalized medicine to treat rare monogenic diseases like lysosomal storage disorders (LSDs) is challenged by complex clinical trial designs, high costs, and low patient numbers. Hundreds of mutant alleles are implicated in most of the LSDs. The diseases are typically classified into 2 to 3 different clinical types according to severity. Moreover, molecular characterization of the ...

A Fabry-Perot wavemeter for analyzing a pulsed laser operating in a single longitudinal mode with an injection-seeding technique has been constructed with an array detector. This wavemeter permits the real-time measurement of both the wavelength and the spectral effectiveness of the laser pulse produced at 10 Hz. The performance of the wavemeter is checked with a frequency-stabilized He-Ne lase...