Positron emission tomography (PET)/computed tomography (CT), which combines the advantages of high sensitivity and specificity of PET and high resolution of CT, is a unique tool for cancer management. PET/CT has been widely used in cancer diagnosis and treatment. The article reviews the recent applications of PET/CT in radiation oncology, with a focus on (18)F-fluorodeoxyglucose (FDG)-PET/CT, a...

Asymptomatic skeletal muscle metastasis in non-small cell lung cancer is a rare event particularly when it is detected at initial staging. This report describes how whole body imaging with [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET)-computed tomography (CT) detected a solitary asymptomatic metastasis to the gluteus maximus muscle in a potentially resectable case of non-smal...

18-Fluoredeoxyglucose position emission tomography and computed tomography (F-18FDG PET/CT) scanning has been useful in the evaluation of malignant disorders and has been extensively used in cancer screening. However, F-18FDG uptake was not found to be specific for cancer diagnosis. Here, we describe increased F-18FDG uptake on PET/CT caused by extensive tuberculous lymphadenitis in a 62-year-o...

Precision Nanomedicine Using Dual Positron Emission Tomography and Magnetic Resonance Temperature Imaging–Guided Photothermal Therapy Min Zhou, Marites Melancon, R. Jason Stafford, Junjie Li, Alpa M. Nick, Mei Tian, Anil K. Sood, and Chun Li* Departments of Cancer Systems Imaging, Interventional Radiology, Imaging Physics, Gynecologic Oncology and Reproductive Medicine, and Center for RNAi and ...

Introduction: Smokers and non-smokers are at the risk of developing lung cancer when exposed to alpha rays as a result of the relatively low levels of radium and radon that may be present in different tobacco species. There is a great interest in studies and research on the radionuclides in narghile tobacco emitting alpha particles to know the relationship between smok...

Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level poss...

Positron emission tomography (PET)/computed tomography (CT) has a growing role in the imaging of many cancers. As our experience has grown over the past number of years so has our understanding for which cancers it is particularly useful. The value of PET/CT at each stage of the cancer journey is different for each cancer. This review attempts to tease out the role of PET/CT in the common cance...

Evasion of apoptosis is one of the six initially proposed hallmarks of cancer, and as such, a method to detect apoptosis in a tumour would be of considerable interest in both clinical trials of new cancer therapeutics, as well as for routine patient management. Activation of caspase-3/7 is a key biomarker of cellular apoptosis. Herein we describe the design, synthesis and initial characterisati...