نتایج جستجو برای: familial mds

تعداد نتایج: 63422  

Journal: :Finite Fields and Their Applications 2018
Baokun Ding Tao Zhang Gennian Ge

Recently, Yaakobi et al. introduced codes for b-symbol read channels, where the read operation is performed as a consecutive sequence of b > 2 symbols. In this paper, we establish a Singleton-type bound on b-symbol codes. Codes meeting the Singleton-type bound are called maximum distance separable (MDS) codes, and they are optimal in the sense they attain the maximal minimum bdistance. Based on...

Journal: :Blood 1993
M Masuya K Kita N Shimizu K Ohishi N Katayama T Sekine A Otsuji H Miwa S Shirakawa

Ten patients with acute leukemia after primary myelodysplastic syndrome (MDS-AL) were examined to clarify the biologic nature of the leukemic cells in comparison with that of de novo acute myelocytic leukemia (AML). The morphologic and cytochemical features of the leukemic cells from all these patients corresponded well to those of de novo AML, and they were diagnosed with MDS-AML. Phenotypical...

2016
Farhad Zaker Naser Amirizadeh Nahid Nasiri Seyed Mohsen Razavi Ladan Teimoori-Toolabi Marjan Yaghmaie Roya Mehrasa

Myelodysplastic syndromes (MDSs) are a clonal bone marrow (BM) disease characterized by ineffective hematopoiesis, dysplastic maturation and progression to acute myeloid leukemia (AML). Methylation silencing of HRK has been found in several human malignancies. In this study, we explored the association of HRK methylation status with its expression, clinical parameters and MDS subtypes in MDS pa...

2016
A J I S Rathnayake H W W Goonasekera V H W Dissanayake

Bone marrow (BM) mesenchymal stem/stromal cells (MSCs) are vital in hematopoiesis. Whether BM-MSCs alter their characteristics in Myelodysplastic Syndromes (MDS) is still controversial. We characterized MSCs of de novo MDS patients in Sri Lanka who have not been reported previously in the literature. We also analyzed MSCs derived from different MDS subtypes. MSCs were culture-expanded, characte...

2009
Stanislav G. Kozmin Yuliya Sedletska Anne Reynaud-Angelin Didier Gasparutto Evelyne Sage

It has been stipulated that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. Using a variety of model multiply damaged sites (MDS), we investigated parameters that govern the formation of DSB during the processing of MDS. Duplexes carrying MDS were inserted into replicative or integrative vector...

2017
Peter Valent Attilio Orazi David P. Steensma Benjamin L. Ebert Detlef Haase Luca Malcovati Arjan A. van de Loosdrecht Torsten Haferlach Theresia M. Westers Denise A. Wells Aristoteles Giagounidis Michael Loken Alberto Orfao Michael Lübbert Arnold Ganser Wolf-Karsten Hofmann Kiyoyuki Ogata Julie Schanz Marie C. Béné Gregor Hoermann Wolfgang R. Sperr Karl Sotlar Peter Bettelheim Reinhard Stauder Michael Pfeilstöcker Hans-Peter Horny Ulrich Germing Peter Greenberg John M. Bennett

Myelodysplastic syndromes (MDS) comprise a heterogeneous group of myeloid neoplasms characterized by peripheral cytopenia, dysplasia, and a variable clinical course with about 30% risk to transform to secondary acute myeloid leukemia (AML). In the past 15 years, diagnostic evaluations, prognostication, and treatment of MDS have improved substantially. However, with the discovery of molecular ma...

Journal: :Blood 2006
Tony A Navas Mani Mohindru Myka Estes Jing Ying Ma Lubomir Sokol Perry Pahanish Simrit Parmar Edwin Haghnazari Li Zhou Robert Collins Irene Kerr Aaron N Nguyen Yin Xu Leonidas C Platanias Alan A List Linda S Higgins Amit Verma

The myelodysplastic syndromes (MDSs) are collections of heterogeneous hematologic diseases characterized by refractory cytopenias as a result of ineffective hematopoiesis. Development of effective treatments has been impeded by limited insights into any unifying pathogenic pathways. We provide evidence that the p38 MAP kinase is constitutively activated or phosphorylated in MDS bone marrows. Su...

Journal: :Expert Syst. Appl. 2010
Byoungsoo Kim

Due to the rapid growth of mobile data service (MDS), research into MDS continuance has recently emerged as an important issue in information systems (IS) and marketing literature. This study develops an integrated model designed to predict a user’s continuance behavior toward MDS based on the expectation–confirmation model (ECM) and the theory of planned behavior (TPB). Empirical data collecte...

2015
Anwarul Islam

Lenalidomide is an immunomodulatory drug which is used to treat patients with MDS with deletion 5q chromosomal abnormality. In 2008, WHO introduced a new disease entity called MDS/MPN. No specific treatment for MDS/MPN subtype has yet been identified. We report a patient with MDS/MPN who responded well to lenalidomide therapy.

H. Ghassemi H. Nowruzi

In the current study, five different atomistic water models (AWMs) are implemented, In order to investigate the impact of AWMs treatment on the water velocity profile and density number. For this purpose, Molecular dynamics simulation (MDS) of Poiseuille flow in a nano-channel is conducted. Considered AWMs are SPC/E, TIP3P, TIP4P, TIP4PFQ and TIP5P. To assessment of the ability of each model in...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید