objective(s):familial mediterranean fever (fmf) is an autosomal recessive disorder characterized by recurrent episodes of fever accompanied by peritonitis, pleurisy, and arthritis. fmf affects mainly mediterranean populations and is caused by mutations in the familial mediterranean fever (mefv) gene. the aim of this study was to identify the frequency and distribution of mefv mutations in irani...

introduction: similar to social and conscious emotions, shame and guilt have gained increasing attention because of their eminent emotional, motivational, and cognitive functions that ultimately guide human beings' perception and behavior. the aim of this study was to assess the relationship between shame and guilt feelings with the dimensions of loneliness (familial, social, and romantic). met...

appendicitis is the most common abdominal disease that requires surgery in the emergency ward. it usually presents as right lower quadrant pain, but may rarely present as left upper quadrant (luq) pain due to congenital anatomical abnormalities of the intestine. we report a patient who complained of persistent luq abdominal pain and was finally diagnosed by computed tomography (ct) as congenita...

conclusions this case highlights the fact that fhr and ghd may coexist, with possible masking effect of one on the other, thereby misleading the approach, posing large impacts on therapy, which has historically been a difficult challenge in fhr patients. introduction coincided familial hypophosphatemic rickets (fhr) and hypopituitarism is a rare condition. growth hormone deficiency (ghd) evalua...

introduction: aortic dissection is a rare condition in young women and usually related with congenital anomalies of aorta and connective tissue disorders. we reported a 34-year-old postpartum woman with aortic dissection. case presentation: the patient complained of respiratory distress and weakness with no abdominal pain or chest pain 20 days after delivery and had no history of hypertension d...

gardner's syndrome is an autosomal dominant inherited disorder. familial polyposis of the colon, osteomas, hypertrophy of the retinal-pigmented layer and a multitude of soft tissue tumors are characteristic features. the syndrome may be presented with colonic or extracolonic symptoms. a 75-year-old male patient presented to al-zahra clinic with diffuse abdominal pain. an abdominal surgery ...

BACKGROUND Previous studies of families with fronto-temporal dementia (FTD) support an autosomal dominant inheritance pattern, but most studies have described genetic transmission in individual families specifically selected for the presence of multiple affected individuals. OBJECTIVE To investigate the familial presentation and inheritance of FTD and related disorders among a large group of ...