background: nepeta dschuparensis bornm (np) is used as a medicinal herb in iran. in traditional medicine, this herb is extensively employed for curing ailments such as cardiovascular diseases. np has antioxidant and anti-inflammatory properties. this project examined the effects of the np extract on cyclooxygenase-2 (cox-2) and interleukin-1β (il-1β) protein levels and its efficacy in neuroprot...

Hypoxia, a deficiency in the levels of oxygen, is common feature most solid tumors and induces many characteristics cancer. Hypoxia associated with metastases strong resistance to radio- chemotherapy, can decrease accuracy cancer prognosis. Non-invasive imaging methods such as positron emission tomography (PET) single-photon computed (SPECT) using hypoxia-targeting radiopharmaceuticals have bee...

Abstract Background Hypoxia-mediated radioresistance is the main obstacle to successful treatment of glioblastoma (GBM). Enhancing hypoxic radiosensitivity and alleviating tumor hypoxia are both effective means improve therapeutic efficacy, combination two highly desirable meaningful. Results Herein, we construct a low-dose pleiotropic radiosensitive nanoformulation consisting high-Z atomic nan...