BACKGROUND AND AIMS There are no available effective therapies for fatigue associated with chronic hepatitis C (CHC). The serotonin antagonist ondansetron has been shown to be effective in the chronic fatigue syndrome. In this randomised, placebo controlled, double blind trial, we investigated the effect of orally administered ondansetron on fatigue in CHC. METHODS Thirty six patients with CH...

PURPOSE OF REVIEW Several studies have investigated fatigue among sarcoidosis patients. The purpose of this review is to analyze published data on the assessment, prevalence, etiology, and treatment of sarcoidosis-associated fatigue. RECENT FINDINGS Fatigue was identified as a prominent problem in sarcoidosis, and its presence was frequently associated with impaired quality of life, compared ...

Recent developments in power electronics technology have spurred interest in the use of renewable energy sources as distributed generation (DG) generators. The key component in DG generators is a grid-connected inverter that serves as an effective interface between the renewable energy source and the utility grid. The multifunctional inverter (MFI) is special type of grid-connected inverter tha...

We develop a tractable model of competition among motivated MFIs. We find that equilibria may or may not involve double-dipping (and consequently default), with there being double-dipping whenever the MFIs are very profit-oriented. Moreover, in an equilibrium with double-dipping, borrowers who double-dip are actually worse off compared to those who do not. Further, for intermediate levels of mo...

BACKGROUND There is a growing need to offer persons with multiple sclerosis (PwMS) possibilities for self-management and to integrate multidisciplinary health data. In 2009-2014 we developed a patient-reported outcome based, interactive, web-based program (MSmonitor) for (self-)monitoring, self-management and integrated, multidisciplinary care in MS. METHODS The notions underlying the MSmonit...

BACKGROUND Chronic fatigue syndrome (CFS) is common and its cause is unknown. AIM To study the prevalence of autonomic dysfunction in CFS, and to develop diagnostic criteria. DESIGN Cross-sectional study with independent derivation and validation phases. METHODS Symptoms of autonomic dysfunction were assessed using the Composite Autonomic Symptom Scale (COMPASS). Fatigue was assessed usin...

Objective: After traumatic brain injury (TBI) or stroke, long-term mental fatigue may occur with significant impact on work and social interactions. With the intention to measure mental fatigue irrespective of neurological illness, we developed the Mental Fatigue Scale (MFS). The scale incorporates affective, cognitive and sensory symptoms, duration of sleep and daytime variation in symptom sev...

1503 Background: Patients with brain cancer develop neurobehavioral dysfunction and fatigue that compromise their performance of daily activities. We report results from evaluating the efficacy and safety of modafinil treatment for tumor/therapy sequelae in this medically fragile patient population. METHODS Patients: 21-65 years old with primary malignant disease or nonmalignant cerebral tumo...

Background & Aims of the Study: Fatigue is one of the most important issues relating with safety and other aspects of human life. To understand fatigue and its relative factors and causes, there is a need to useful instruments, such as self-reported scales. The purpose of this study is to identify and present useful self-reported scales to measure fatigue. Materials & Methods: Data were extrac...

OBJECTIVE Fatigue is an important outcome for patients with rheumatoid arthritis (RA). The purpose of this study was to identify the scales being used to measure RA fatigue, and to systematically examine the evidence for their validation. METHODS Articles measuring fatigue in RA were sought using the terms RA and fatigue, and RA and tiredness, plus scale, questionnaire, inventory, and checkli...