An enzymatic method has been developed for the measurement of malonyl-CoA in perchioric acid extracts of liver. With this method the relative activities of acetyl-CoA carboxylase and fatty acid synthetase have been studied in vivo by comparing the diet-induced changes in malonyl-CoA concentrations with rates of 3Hz0 incorporation into fatty acids. Malonyl-CoA concentrations were low in the fat-...

The aim of this study was to determine the effect of fish meal and mineral-vitamin premix, supplementing organic diets, on the performance of pigs and some meat and blood characteristics. The experiment was conducted on an organic pig fattening farm. The study involved 120 pigs with an approximate 25 kg body weight. Animals were divided into 3 groups, kept in pens, 10 animals each. Group I (con...

Krag, Aleksander, Lene Simonsen, Jens H. Henriksen, Lone Ottesen, and Flemming Bendtsen. Effect of meal and propranolol on whole body and splanchnic oxygen consumption in patients with cirrhosis. Am J Physiol Gastrointest Liver Physiol 291: G8–G15, 2006. First published February 23, 2006; doi:10.1152/ajpgi.00315.2005.—Our aim was to measure whole body energy expenditure after a mixed liquid mea...

With increasing recognition of the pivotal role of vascular dysfunction in the progression of atherosclerosis, the vasculature has emerged as an important target for dietary therapies. Recent studies have indicated that chronic fatty acid manipulation alters vascular reactivity, when measured after an overnight fast. However, individuals spend a large proportion of the day in the postprandial (...

The effect of pre-exercise meal composition on metabolism and performance in cycling were investigated in a crossover study. Twelve competitive cyclists ingested high-fat, high-carbohydrate, or high-protein meals 90 min before a weekly exercise test. The test consisted of a 1-hour pre-load at 55% peak power, five 10-min incremental loads from 55 to 82% peak power (to measure the peak fat-oxidat...

The recycling of rendered animal products back into the feed of ruminant livestock species has had a positive impact both on the efficiency of livestock production and the availability of meat and milk for consumers at an affordable price. Rendered animal products are distinguished by a high protein content containing amino acids that resist microbial degradation in the rumen, and for extracted...

Preprocessed fatty foods often contain calories added as a fat emulsion stabilized by emulsifiers. Emulsion stability in the acidic gastric environment can readily be manipulated by altering emulsifier chemistry. We tested the hypothesis that it would be possible to control gastric emptying, CCK release, and satiety by varying intragastric fat emulsion stability. Nine healthy volunteers receive...

Consumption of a high fat meal can increase neutrophilic airway inflammation in asthma subjects. This study investigates the molecular mechanisms driving airway neutrophilia following a high fat meal in asthmatics. Subjects with asthma (n = 11) and healthy controls (n = 8) consumed a high-fat/energy meal, containing total energy (TE) of 3846 kJ and 48 g of total fat (20.5 g saturated). Sputum w...

Test meals are invariably used in the 13C-urea breath test (UBT) but their effect on the intragastric distribution and gastric residence time of urea given in the test is unknown. The site of Helicobacter pylori urease measured in the test is unknown and whether the test measures total or regional gastric urease is uncertain. This study reports the results of paired UBTs with simultaneous gastr...