BACKGROUND Ga-[1,4,7,10-tetraazacyclododecane-N,N',N″,N'″-tetraacetic acid]-d-Phe1,Tyr3-octreotate (DOTATATE) positron emission tomography (PET) is commonly used for the visualization of somatostatin receptor (SSTR)-positive neuroendocrine tumors. SSTR is also known to be expressed on macrophages, which play a major role in inflammatory processes in the walls of coronary arteries and large vess...

PURPOSE To evaluate the appropriate post-injection timing for hand-held-gamma-ray-detecting probe (GDP) scanning for the intraoperative detection of malignancy after preoperative F-18 FDG (FDG) injection. METHODS Patient study with superficially located cancer was performed on three patients before operation by dual-phase whole-body PET at 2 and 6-7 hr post-injection of FDG (370 MBq), and by ...

AIM To determine the significance and need for investigation of incidental prostatic uptake in men undergoing 18F-labelled fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for other indications. METHODS Hospital databases were searched over a 5-year period for patients undergoing both PET/CT and prostate magnetic resonance imaging (MRI). For the initial a...

We describe a patient with newly diagnosed limy cancer. Staging was performed with CT and mediastinoscopy. FDG PET scan was performed and confirmed increased metabolic activity in the primary tumor as well as the hilar lymph node. Seven months after initial presentation, the patient was found to have two lytic lesions in the pelvis on plain radiograph. Hone scan was negative but PET demon...

2.87 0.82 versus 1.55 0.17; 18F-FDG: 1.58 0.21 versus 1.30 0.13; both P 0.001). 18F-NaF uptake displayed a progressive rise with valve severity (r 0.540, P 0.001), with a more modest increase observed for 18F-FDG (r 0.218, P 0.001). Among patients with aortic stenosis, 91% had increased 18F-NaF uptake ( 1.97), and 35% had increased 18F-FDG uptake ( 1.63). A weak correlation between the activiti...

BACKGROUND We found that (18)F-2-fluoro-2-deoxy-D-glucose ((18)F-FDG) uptake in malignant lesion was enhanced, and it was decreased in the inflammatory lesion after the use of peroxisome proliferator activated receptor-γ (PPAR-γ) agonist in our previous preclinical study. The purpose of this study was to investigate the effect of PPAR-γ agonist on malignant lesions in clinical (18)F-FDG positro...

UNLABELLED A 3 years old female patient underwent resection and chemotherapy for a yolk sac tumor of the retroperitoneum. Two years later, fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) showed high uptake in the right ischiopubic synchondrosis (IPS), which had a radiolucent structure on CT. The structure showed contrast enhancement on magnetic...

OBJECTIVE The sensitivity of FDG at PET examination of Hepatocellular Carcinoma (HCC) is restricted. In a few studies, all done in Oriental patients, PET-examination with (11)C-acetate has shown a higher accuracy than with FDG. In the current study, the uptake of (11)C-acetate has been compared with the uptake of FDG in the primary HCC in a cohort of Occidental patients. MATERIAL AND METHODS ...

BACKGROUND [18F]2-deoxy-2-fluoroglucose (FDG) is widely used as a tracer for glucose uptake in ischemic heart muscle. We tested the effects of low-flow ischemia and reperfusion on the ratio of tracer/tracee (lumped constant, LC). METHODS AND RESULTS Isolated working rat hearts were perfused with Krebs-Henseleit buffer containing only glucose 5 mmol/L (group 1) or glucose 5 mmol/L plus oleate ...

INTRODUCTION FDG PET/CT is believed to be crucial in oncology, but its limited specificity represents a challenge. Prosthetic meshes used for repair abdominal defects may lead to false-positives FDG PET/CT uptake, over staging malignancies and inducing inappropriate treatments. A false-positive FDG PET/CT uptake mimicking metastatic disease during the follow-up of a previously treated metastati...