Syntheses of N,N'-phenyltetrazole podands link with aliphatic chains containing oxygen, nitrogen and sulphur atoms, are described. The complexing properties of these compounds towards metal cations (Fe2+, Cu2+, Zn2+, Co2+, Ni2+) were investigated by absorption and infrared spectroscopy. The UV-Vis titrations were performed to estimate the stability constant values of the respective complexes wi...

Diclofenac sodium was extensively used for treating arthritis, osteoarthritis and skeletal muscular injuries, which ultimately caused troubles aquatic organisms as well human beings. In this study, homogeneous catalytic advanced oxidation processes, including Fe2+/persulfate, Fe2+/peroxymonosulfate Fe2+/H2O2, were the degradation of diclofenac in water, without using UV-C light. About 89, 82 54...

Serum albumin protein plays a key role in the transportation and distribution of bioactive species including metal ions metal-based drugs and, therefore, nature their binding could provide important insight for development new drugs. In present investigation, interactions bovine serum (BSA) with three biologically ions: Pt4+, Ir3+ Fe2+ were screened using easy-to-use cost-effective Fourier-Tran...

In order to survive in an oxygen environment, aerobic organisms have developed numerous mechanisms to protect against oxygen radicals and singlet oxygen. One such mechanism, which appears to have attained particular significance during primate evolution, is the direct scavenging of oxygen radicals, singlet oxygen, oxo-haem oxidants and hydroperoxyl radicals by uric acid. In the present paper we...

The absorption of metal ions in the mammalian single-stomached gut is fortunately highly selective, and both luminal and tissue regulation occur. Initially, assimilation of metal ions in an available form is facilitated by the intestinal secretions, chiefly soluble mucus (mucin) that retards hydrolysis of ions such as Cu, Fe and Zn. Metal ions then bind and traverse the mucosally-adherent mucus...

Dried and wet mouse fibroblast monolayers with labeled collagenous substrate were used to study the effects of lipoteichoic acid (LTA) on cellular prolyl hydroxylase activity. LTA is a scavenger of cations, and Fe2+ is essential for prolyl hydroxylase activity. Surprisingly, addition of LTA to dried monolayers resulted in increased prolyl hydroxylase activity, whereas preincubation of Fe2+ with...

A triple-decker complex of tungsten, [(Cp*W)2{μ-η6:η6-B4H4Co2(CO)5}(H)2] (1; Cp* = η5-C5Me5), with a planar middle deck has been isolated by thermolysis an in situ formed intermediate from the reaction Cp*WCl4 and LiBH4 Co2(CO)8. In addition, we have also another complex, [(Cp*W)2{μ-η6:η6-B5H5Fe(CO)3}(H)2] (4), having puckered central ring, similar Fe2(CO)9. Clusters 1 4 are unprecedented examp...

Iron (2+ and 3+) is believed to transfer through the three-fold channels in the ferritin shell during iron deposition and release in animal ferritins. However, the rate of iron transit in and out through these channels has not been reported. The recent synthesis of [Fe(CN)6]3-, Prussian Blue (PB) and desferrioxamine (DES) all trapped within the horse spleen ferritin (HoSF) interior makes these ...

This study presents an analysis of a set iron oxides nanoparticles (NPs) (γ-Fe2O3, α-FeOOH, δ-FeOOH, 5Fe2O3·9H2O, and Fe3O4) as potential candidates for ferroptosis therapy in terms phase state, magnetic characteristics, the release Fe2+/Fe3+ ROS mediators. Due to values saturation magnetization Fe3O4 (31.6 emu/g) γ-Fe2O3 (33.8 emu/g), well surface area these particles (130 123 m2/g), it is pos...