BACKGROUND Birth asphyxia is one of the commonest causes of neonatal morbidity and mortality in developing countries. Together with prematurity and neonatal sepsis, they account for over 80% of neonatal deaths. AIM To determine the incidence and mortality rate of birth asphyxia in Warri Niger Delta of Nigeria. MATERIALS AND METHOD Recovery of case notes of all the newborn babies seen from J...

background: asphyxia is a medical condition in which placental or pulmonary gas exchange is impaired or they cease all together, typically producing a combination of progressive hypoxemia and hypercapnea. objective: in addition to regional differences in its etiology; it is important to know its risk factors. materials and methods: this is a case-control study, all neonates born from may 2002 t...

OBJECTIVE Perinatal asphyxia may result in hypoxic damage in various body organs, especially in the central nervous system. It could induce cascade of biochemical events leading to the cell death and metabolic changes, eventually may increase plasma ammonia levels. The purpose of this study was to determine the prevalence of hyperammonemia in neonates with asphyxia and to find the relationship ...

The aim of this review is to present the summarisation of the knowledge about biochemical and clinical changes that occur under the influence of asphyxia as well as about the treatment. Results of experimental works in animal models bring us the explanation about many postasphyxiated changes and help us to understand the pathophysiological changes and consequences of asphyxia. The authors prese...

BACKGROUND Fetal hypoxia is an important determinant of neonatal encephalopathy caused by birth asphyxia, in which hypoxia-induced free radical formation plays an important role. HYPOTHESIS Maternal treatment with allopurinol, will cross the placenta during fetal hypoxia (primary outcome) and reduce S-100B and free radical formation (secondary outcome). METHODS In a randomized, double-blind...

The relation between fetal distress and the subsequent condition at birth was studied in 2791 pregnancies. Fetal distress was defined as a heart rate greater than 160 or less than 120/min between uterine contractions, with or without meconium-stained liquor. Infants of 28 to 42 weeks' gestational age were examined at 1 and 5 minutes after birth when the heart rate, respiration, and skin colour ...

The activity of liver enzymes, namely ALT, AST and LDH was evaluated in 68 cases of Pregnancy induced hypertension along with 56 normal primiparous subjects. The activity of all 3 enzymes were found to be elevated significantly in subjects with Pregnancy induced hypertension with respect to control subjects. Fetal birth weight was found to be significantly decreased in former condition and corr...

Background: Asphyxia is one the most important causes of neonatal mortality and morbidity. It is suggested that magnesium may have a protective role against cellular damage during hypoxic brain insult, or change effect post-asphyxia consequences. Our study was performed for comparison of serum magnesium in neonates with and without asphyxia.    Methods: This study was done in Neona...