Within the past few years there has arisen a renewed interest in that group of bacterial forms designated as the "Pleuropneumonia Group," the prototype of which is Pleuropneumonia bovum, first described by Nocard and Roux in 1898, and for many years regarded as a virus because of its filterability. However, the cultivation of this organism on cell-free media, and the later complete description ...

A child with congenital hemolytic anemia, extreme microcytosis and bizarre red cell morphology has been studied. Splenectomy at the age of 21 mo greatly improved the hemolytic anemia, although red cell morphology was unchanged. Aniso- and poikilocytosis were marked on a stained smear, and there were many small hyperchromatic cells of irregular shape. The MCV of 25 cu mu was very low and the MCH...

Aluminium (Al) is absorbed from a variety of foodstuffs and medications. Its major route of elimination from the body is in the urine. However, current knowledge concerning its glomerular filtration and, more particularly, its reabsorption/secretion is fragmentary. Most (80-90%) of Al in the plasma is normally bound to protein (mainly transferrin) and is therefore unfilterable; the remainder is...

BACKGROUND RBC components collected from donors with sickle cell trait frequently occlude WBC-reduction filters. In vitro, sickle trait RBCs have the potential for sickle Hb (Hb S) polymerization at low oxygen saturations and high Hb concentrations. STUDY DESIGN AND METHOD To determine if the low pH and high osmolarity of the CP2D used in the collection contributed to filter failures, the fil...

OBJECTIVE To evaluate if viscoelastic properties of blood influence suffering sudden sensorineural hearing loss and the capacity to respond after a specific therapy. PATIENTS AND METHODS A longitudinal prospective study included 85 ears bearing sudden deafness. In them, the mean hearing loss compared to the healthy ear and the recovery ratio were measured at the onset and 6 months after a tre...

−A biomaterial was successfully synthesized from Plantago ovata by using an FeCl3-induced crude extract (FCE). The potential of FCE to act as a natural coagulant was tested for the pretreatment of real textile wastewater. Tests were performed to evaluate the effects of FCE quantity, salt concentration, and wastewater pH on chemical oxygen demand (COD) reduction during a coagulation/flocculation...

BACKGROUND The development of integrated continuous biomanufacturing processes faces a significant challenge when the parameters for design process cannot be accurately estimated from those batch experiments. Process is even more challenging if outcome one unit operation highly influences performance subsequent one, such as in harvesting precipitate by filtration. In case protein precipitation,...

A filtration devise was developed to assess compressibility of fouling layers in membrane bioreactors. The system consists of a flat sheet membrane with air scouring operated at constant transmembrane pressure to assess the influence of pressure on resistance of fouling layers. By fitting a mathematical model, three model parameters were obtained; a back transport parameter describing the kinet...

Dematin is an actin-binding and bundling protein of the erythrocyte membrane skeleton. Dematin is localized to the spectrin-actin junctions, and its actin-bundling activity is regulated by phosphorylation of cAMP-dependent protein kinase. The carboxyl terminus of dematin is homologous to the "headpiece" domain of villin, an actin-bundling protein of the microvillus cytoskeleton. The headpiece d...

The possible role of white blood cells in tissue ischaemia has attracted recent interest. White blood cells can block narrow vessels, particularly if perfusion pressure is reduced or if the cells become activated. To investigate the role of white blood cells in ischaemia microfiltration techniques were used to measure the flow properties of these cells in patients with severe leg ischaemia befo...