False positives in a Genome-Wide Association Study (GWAS) can be effectively controlled by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population structure and kinship among individuals to adjust association tests on markers; however, the adjustment also compromises true positives. The modified MLM method, Multiple Loci Linear Mixed Model (MLMM), incorporates mul...

A robust fixed-lag smoothing approach is proposed in the case there a mismatch between nominal model and actual model. The resulting smoother characterized by dynamic game two players: one player selects least favorable prescribed ambiguity set, while other minimizing error with respect to We propose an efficient implementation of smoother. Moreover, we characterize corresponding over finite ti...

This paper analyses the impact of sanctions against Iran in addition to other country-specific determinants on intra-industry trade between Iran and Shanghai Cooperation Organization (SCO) countries over the period 1997-2013. By disentangling total intra-industry trade (IIT) into horizontal and vertical IIT and after investigating bilateral trade pattern between Iran and SCO countries, determin...

in this paper, a new alternative method for order reduction of high order systems is presented based on optimization of multi objective fitness function by using harmony search algorithm. at first, step response of full order system is obtained as a vector, then, a suitable fixed structure considered for model order reduction which order of original system is bigger than fixed structure model. ...

Controllability problems for different types of nonlinear dynamical systems with delays in control has been studied by several authors with the help of different fixed point theorems [1-15]. In particular in the paper [7] the notion of measure of noncompactness of a set and Darbo’s fixed point theorem are used for the study of the relative controllability for nonlinear systems with lumped multi...

It has been put forward that the existence of a non-Gaussian fixed point in general relativity might cure the ultraviolet problems of this theory in a quantum description. Such a fixed point is connected to an effective running of the gravitational coupling. We calculate the effect of such an effective coupling on the black hole production cross-section in models with large extra dimensions.

context: to evaluate treatment success and hypothyroidism following main methods of radioiodine therapy of toxic nodular goiter (tng); calculated versus fixed dose and high versus low dose of radioiodine. evidence acquisitions: we searched medline and scopus databases from inception till july 2013, for clinical trials that compared two different methods of radioiodine administration in tng. the...

Using a dynamic systems model for the Simple Genetic Algorithm due to Vose, we analyze the fixed point behavior of the model without crossover applied to functions of unitation. Unitation functions are simplified fitness functions that reduce the search space into a smaller number of equivalence classes. This reduction allows easier computation of fixed points. The effect of model fixed points ...