This paper presents the requirements analysis for integrated information system models to support corporate planning and control tasks. Corporate planning is a heterogeneous, dynamic, and distributed domain comprising of strategy analysis, process reengineering, and change management. Implementation of such a model will require a multi-tiered approach with a rich and flexible model-based framew...

Attachment of a flexible coil on the mid-part of a rigid rod block generates T-shaped rod-coil block molecules that self-assemble into a stepped column. These layers, in turn, self-curve into a spiral column with tunable core structure in the solid state.

As the core component of the sense of touch, flexible pressure sensors are critical to synchronized interactions with the surrounding environment. Here, we introduce a new type of flexible capacitive pressure sensor based on a template of electrodes, with a one-dimensional pyramid micropatterned structure on a Polydimethylsiloxane (PDMS) substrate and a dielectric layer of polystyrene (PS) micr...

context and for a given individual to, consequently, improve the individual’s performance on a specific task. The wearable (AR) system architecture should also be designed as an extendable, flexible, interoperable, reusable, and scalable infrastructure to support the integration of additional components without impacting the core system/software architecture design and to facilitate standard da...

The core-set approach is a discretization method for Markov state models of complex molecular dynamics. Core sets are disjoint metastable regions in the conformational space, which need to be known prior to the construction of the core-set model. We propose to use density-based cluster algorithms to identify the cores. We compare three different density-based cluster algorithms: the CNN, the DB...

As an emerging cutting-edge area, the anisotropic assembly of isotropic nanoparticles provides not only a unique but also a convenient pathway for constructing materials with novel structures and functions. However, examples of the anisotropic assembly of isotropic nanoparticles are still limited. In particular, methods that can delicately control the assembly of isotropic nanoparticles for the...

Almost all modern proteins possess well-defined, relatively rigid scaffolds that provide structural preorganization for desired functions. Such scaffolds require the sufficient length of a polypeptide chain and extensive evolutionary optimization. How ancestral proteins attained functionality, even though they were most likely markedly smaller than their contemporary descendants, remains a majo...

Blooms of the potentially toxic cyanobacterium Microcystis are increasing worldwide. In the Laurentian Great Lakes they pose major socioeconomic, ecological, and human health threats, particularly in western Lake Erie. However, the interpretation of "omics" data is constrained by the highly variable genome of Microcystis and the small number of reference genome sequences from strains isolated f...

Delta-oriented programming (DOP) is a modular approach for implementing software product lines. Delta modules generalize feature modules by allowing removal of functionality. However, DOP requires to select one particular product as core product from which all products are generated. In this paper, we propose pure deltaoriented programming (Pure DOP) that is a conceptual simplification of tradi...