In the current study, floating dosage form containing acyclovir was developed to increase its oral bioavailability. Effervescent floating tablets containing 200 mg acyclovir were prepared by direct compression method with three different rate controlling polymers including Hydroxypropyl methylcellulose K4M, Carbapol 934, and Polyvinylpyrrolidone. Optimized formulation showed good floating prope...

One of the most common dental anomalies is dens invaginatus. As the name indicates, it is an invagination of the coronary or root surface, bounded by enamel, which can be so profound as to simulate the appearance of a tooth inside another. Usually occurs in permanent maxillary lateral incisors, followed by maxillary central incisors, premolars, canines and less frequently molars. In this articl...

The original work [25] is here reconsidered, so many years after. The old text has been revised, plus several considerations have been added, in order to clarify some controversial aspects of the work, and to envision possible developments. A section has been added, to review the effects of the original paper. The study addresses the problem of precision in floating-point (FP) computations. A m...