Forestier (1929) first used gold salts to treat rheumatoid arthritis (RA), and controlled studies (e.g. Empire Rheumatism Council, 1960, 1961) later confirmed their effectiveness. An empirical schedule of treatment (conventional chrysotherapy) evolved, using 50 mg. monthly, but this might be further improved if dosage could be adjusted for each patient according to the serum level of gold. Atom...
