an oral suspension could a suitable dosage form for the geriatric patients. the calcium alginate coated ion exchange resinate of propranolol hydrochloride were prepared using amberlite ir-120 by solvent evaporation. microcapsules of propranolol hydrochloride resinate were prepared by solvent evaporation technique,the suspensions were prepared by using deionised water as the vehicle. methyl cell...

A fast method for the calculation of residue contributions to protein solvation is presented. The approach uses the exposed polar and apolar surface of protein residues and has been parametrized from the fractional contributions to solvation determined from linear response theory coupled to molecular dynamics simulations. Application of the method to a large subset of proteins taken from the Pr...

Understanding the effect of characteristics formulation and process parameters on physicochemical properties a pharmaceutical product is very significant for development solid dosage forms, as knowledge gained small scale batches in early phase used later phases lifecycle or other products. One approaches gaining better understanding effects production quality finished to apply systematical app...

Our recent studies show that chronic oral nicotine partially protects against striatal damage in 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP)-treated nonhuman primates. To identify the cellular changes associated with this protective action, we investigated the effects of nicotine treatment on stimulus-evoked dopamine release, dopamine turnover, and synaptic plasticity in striatum from le...

We investigate the profile of the blowing up solutions to the nonlinear nonlocal system (FDS) u′(t) + Dα0+(u − u0)(t) = |v(t)|q, t > 0, v′(t) + Dβ0+(v − v0)(t) = |u(t)|p, t > 0, where u(0) = u0 > 0, v(0) = v0 > 0, p > 1, q > 1 are given constants and Dα0+ and Dβ0+ , 0 < α < 1, 0 < β < 1 stand for the Riemann-Liouville fractional derivatives. Our method of proof relies on comparisons of the solu...

Ethanol is largely used as a solvent in the synthesis of varnishes and perfumes. It is also used as a preservative for biological products, fuel, and gasoline additives. Anethanol-water mixture, normally obtained by fractional distillation</span...

Fractional release factors of long-lived halogenated organic compounds in the tropical stratosphere J. C. Laube, A. Engel, H. Bönisch, T. Möbius, W. T. Sturges, M. Braß, and T. Röckmann Institute for Atmospheric and Environmental Sciences, University of Frankfurt, Germany School of Environmental Sciences, University of East Anglia, UK Institute for Marine and Atmospheric Research, Utrecht Unive...