PURPOSE Transferring the bone morphogenetic protein 2 (BMP-2) genes into the tissues or cells can improve the bone healing of the fracture has been widely accepted. We evaluated the efficiency of using gene gun to transfer the BMP-2 gene thereby affected the healing of a fractured bone. METHODS The vector coding for BMP-2 was constructed by a non-replicating encephalo-myocarditis virus (ECMV)...

INTRODUCTION Fracture healing is a complex biological process involving inflammation, granulation, callus formation, and bone modeling/remodeling. Optimal fracture healing results in complete restoration of bone structure and function to the pre-fracture levels. However, some fractures are associated with a high risk of delayed union, non-union and other complications. This leads to significant...

OBJECTIVE Vertebroplasty is an effective treatment for vertebral compression fracture, but may progress gradual vertebral height decrease in spite of vertebroplasty. Gradual vertebral height decrease also may induce aggravation of kyphotic change without severe pain. The purpose of this study was to evaluate risk factors for gradual vertebral height decrease in the absence of recurrent severe b...

Langerhans cell histiocytosis (LCH) is rare in the adult population and even rarer with jaw involvement. The current study presents the case of a 39-year-old male who complained of recurrent pain, swelling of the gingiva and an occasional pus-like discharge in the right mandible for one year. The patient was previously prescribed antibiotics, but this did not resolve the problem. An initial pan...

ABSTRACT A 47-year-old gentleman, with underlying seborrhoeic dermatitis that was treated with steroid therapy, and hepatitis B, presented with pain in his right hip. He was diagnosed with stage 2 osteonecrosis of the right hip (Ficat and Arlet classification). Core decompression and bone grafting was performed but recovery was complicated by a surgical site infection. Wound debridement, remova...

Back ground: The clavicle is complex bone, and is most frequently fractured bone of human skeleton. Most of the factures occur at the middle third of the shaft of the bone. The present study was done to measure in length and angles (medial and lateral angles) of clavicle. The angles of clavicle are very important for anatomists, orthopedicians, surgeons and forensic anthropologists. 60 dry clav...