a green and efficient one-pot, four-component synthesis of 6-amino-4-aryl-3-methyl-2,4-dihydropyrano[2,3- c ]pyrazo-carbonitrile derivatives catalyzed by borax in water is described. this method provides several advantages such as environmental friendliness, shorter reaction time, excellent yields, and simple workup procedure. the in vitro cytotoxic activity of the synthesized test compounds wa...

a mixture of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride is used for the symptomatic treatment of common cold. in this study, a derivative spectrophotometric method based on zero-crossing technique was proposed for simultaneous determination of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride. determination of these drugs was perf...

Upper and lower bounds on cell counts in cross-classifications of nonnegative counts play important roles in a number of practical problems, including statistical disclosure limitation, computer tomography, mass transportation, cell suppression, and data swapping. Some features of the Frechet bounds are well known, intuitive, and regularly used by those working on disclosure limitation methods,...

We present a new approach to treat nonlinear operators in reduced basis approximations of parametrized evolution equations. Our approach is based on empirical interpolation of nonlinear differential operators and their Frechet derivatives. Efficient offline/online decomposition is obtained for discrete operators that allow an efficient evaluation for a certain set of interpolation functionals. ...

We develop a non-anticipative calculus for functionals of a continuous semimartingale, using an extension of the Ito formula to path-dependent functionals which possess certain directional derivatives. The construction is based on a pathwise derivative, introduced by B Dupire, for functionals on the space of right-continuous functions with left limits. We show that this functional derivative ad...

for fr$acute{mathbf{text{e}}}$chet algebras $(a, (p_n))$ and $(b, (q_n))$, a linear map $t:arightarrow b$ is textit{almost multiplicative} with respect to $(p_n)$ and $(q_n)$, if there exists $varepsilongeq 0$ such that $q_n(tab - ta tb)leq varepsilon p_n(a) p_n(b),$ for all $n in mathbb{n}$, $a, b in a$, and it is called textit{weakly almost multiplicative} with respect to $(p_n)$ and $(q_n)$,...