BACKGROUND There is clear evidence from numerous randomized trials and their meta-analyses that aspirin reduces risks of first myocardial infarction (MI). Recent data also suggest that other nonsteroidal anti-inflammatory drugs (NSAIDs) may interfere with this benefit of aspirin. METHODS AND RESULTS We performed subgroup analysis from a 5-year randomized, double-blind, placebo-controlled tria...

OBJECTIVES The goal of this study was to determine, in patients with a recent myocardial infarction (MI) and residual wall motion abnormalities within the distribution of the infarct-related artery, whether normal perfusion by myocardial contrast echocardiography (MCE) would accurately predict recovery of segmental left ventricular (LV) function. BACKGROUND Left ventricular dysfunction after ...

With a binary response Y, the dose-response model under consideration is logistic in flavor with pr(Y=1 | D) = R (1+R)(-1), R = λ(0) + EAR D, where λ(0) is the baseline incidence rate and EAR is the excess absolute risk per gray. The calculated thyroid dose of a person i is expressed as Dimes=fiQi(mes)/Mi(mes). Here, Qi(mes) is the measured content of radioiodine in the thyroid gland of person ...

BACKGROUND A consistent relationship between metabolic syndrome (MS) and myocardial infarction (MI) has been demonstrated. We evaluated the effect of bezafibrate retard, a fibric acid derivative, on the incidence of MI in patients with MS enrolled in the Bezafibrate Infarction Prevention (BIP) study. METHODS Patients who displayed at least 3 of the following 5 risk factors were considered to ...

CMV infection is responsible for acceleration of immune senescence and linked to systemic pathologies, including cardiovascular diseases. In this study, we investigated differences in the immune response between CMV-seropositive and seronegative patients undergoing primary percutaneous coronary intervention (PPCI) for acute myocardial infarction (MI). Peripheral blood samples were taken at six ...

INTRODUCTION  rs9982601 (C>T) is a polymorphism of the noncoding region between the SLC5A3/MRPS6 and KCNE2 genes. It has been shown to be associated with early-onset myocardial infarction (MI) with T as a risk allele. OBJECTIVES  The aim of our study was to investigate the association of the rs9982601 polymorphism with long-term overall mortality from MI and prevalence of MI in a Polish popul...

To the Editor: I read with great interest the article by Tsukamoto and Ohara who reported the temporal worsening of sleep-disordered breathing (SDB) in patients with acute coronary syndrome (ACS).1 The authors stated that SDB in the acute phase of myocardial infarction (MI) has not been well analyzed before and that there are no previous reports documenting changes in the severity of SDB during...

Two of the most promising approaches to fighting the state explosion problem are abstraction and compositional verification. In this work we join their forces to obtain a novel fully automatic compositional technique that can determine the truth value of the full μ-calculus with respect to a given system. Given a system M = M1||M2, we view each component Mi as an abstraction Mi↑ of the global s...