نتایج جستجو برای: functional impacts

تعداد نتایج: 717400  

Journal: :F1000Research 2022

Background: Considering protein mutations in their biological context is essential for understanding functional impact, interpretation of high-dimensional datasets and development effective targeted therapies personalized medicine. Methods: We combined the curated knowledge biochemical reactions from Reactome with analysis interact...

Journal: :Blood 2012
Sohini Sanyal Stéphane Egée Guillaume Bouyer Sylvie Perrot Innocent Safeukui Emmanuel Bischoff Pierre Buffet Kirk W Deitsch Odile Mercereau-Puijalon Peter H David Thomas J Templeton Catherine Lavazec

Infection of erythrocytes with the human malaria parasite, Plasmodium falciparum, results in dramatic changes to the host cell structure and morphology. The predicted functional localization of the STEVOR proteins at the erythrocyte surface suggests that they may be involved in parasite-induced modifications of the erythrocyte membrane during parasite development. To address the biologic functi...

2014
Yanqi Yang Chong Ren

Although functional appliances have been widely adopted for clinical modulation of mandibular growth for nearly a century, the underlying regulatory mechanism of mandibular condyle growth have been under investigation. Over these years, studies have been focused on both the natural growth of mandibular condyle and its growth modulation by functional appliances at cellular and molecular levels. ...

Journal: :IJSSOE 2015
Mokdad Arous Djamel-Eddine Saïdouni Jean-Michel Ilié

Considering both qualitative and quantitative aspects in the same modeling approach enhances coherency when analyzing concurrent system properties. Moreover, the impacts of changes related to functional and temporal features are generally better highlighted. In this paper, the authors present their approach to model and analyze behavioral and temporal properties of true concurrency systems. Com...

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