نتایج جستجو برای: fuzzy ctl
تعداد نتایج: 98341 فیلتر نتایج به سال:
HLA diversity is seen as a major challenge to CTL vaccines against HIV. One current approach focuses on "promiscuous" epitopes, presented by multiple HLA alleles from within the same HLA supertype. However, the effectiveness of such supertype vaccines depends upon the functional equivalence of CTL targeting a particular epitope, irrespective of the restricting HLA. In this study, we describe th...
CD8 T cell or cytotoxic T lymphocyte (CTL) responses are an important branch of the immune system in the fight against viral infections. The dynamics of anti-viral CTL responses have been characterized in some detail, both experimentally and with mathematical models. An interesting experimental observation concerns the timing of CTL responses. A recent study reported that in pneumonia virus of ...
The nature of alloreactivity to MHC molecules has been enigmatic, primarily because of the observation that allogeneic responses are considerably stronger than syngeneic responses. To better determine the specificity potential of allogeneic responses, we have generated alloreactive CTL specific for exogenous, viral-derived peptide ligands. This approach allowed us to critically evaluate both th...
Recognition by CD8(+) T lymphocytes (CTL) of epitopes that are derived from conserved gene products, such as Gag and Pol, is well documented and conceptually supports the development of epitope-based vaccines for use against diverse HIV-1 subtypes. However, many CTL epitopes from highly conserved regions within the HIV-1 genome are highly variable, when assessed by comparison of amino acid sequ...
Cytotoxic lymphocyte (CTL) responses of unprimed NZB spleen cells peaked on day 4 of culture as did cells from primed NZB or BALB/c mice. In contrast, primary BALB/c and DBA/2 responses peaked on day 6 of culture. Thus, NZB CTL generation was similar to the accelerated in vitro generation of CTL from the spleen cells of alloantigen-primed NZB and BALB/c mice. To evaluate the kinetics of these C...
This paper analyses the risk of failure associated with control methods for overvoltages due to compact transmission-line (CTL) energization. The Approximate Statistical Insulation Coordination Method is applied different verify which will be very suitable long CTL. results are analyzed according devices and configurations using pre-insertion resistor, controlled switching and, surge arrester. ...
This study aims to reveal the effect of using school television media and Contextual Teaching Learning (Ctl) learning methods on children's cognitive abilities. research is a quantitative research. The sampling technique used was Cluster Random Sampling. sample amounted 22 students in group B. test results instrument showed that reliability ability 0.921. data analysis simple regression analysi...
This study presented the effects of carrier-transporting layer (CTL) on electroluminescence (EL) performance a blue phosphorescent organic light-emitting diodes (PHOLEDs) with electron transporting host based three kinds electron-transporting layers (ETLs) including 3-(4-biphenyl-yl)-4-phenyl-5-(4-tert-butylphenyl)-1,2,4-triazole (TAZ), diphenyl-bis[4-(pyridin-3-yl)phenyl]silane (DPPS) and 1,3,...
Abstract Background and Hypothesis Environmental stressors may influence immune surveillance in B lymphocytes stimulate autoimmune responses via epigenetic DNA methylation modifications schizophrenia (SCZ). Study Design A total of 2722 Chinese Han origin subjects were recruited this study (2005-2011), which including a discovery follow-up cohort with 40 remitters SCZ (RSCZ), non-remitters (NRSC...
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