BACKGROUND Hemorrhagic fever with renal syndrome (HFRS) is an important infectious disease in Hebei Province. At present, cases from the northeast regions of the province account for >80% of the total incidences. However, studies that examine the region-specific genetic variations of the Hantavirus (HV), the causative pathogen for HFRS, have been lacking. METHODS Rodents were collected in nor...

Hypoxic vasoconstriction (HV) is an intrinsic response of mammalian pulmonary vascular smooth muscle (VSM). In the present study, HV was examined by myography of vessel rings from three primitive vertebrates: New Zealand hagfish (NZH), Pacific hagfish (PH), and sea lamprey (SL). Hypoxia dilated pre-gill arteries (ventral aorta, afferent branchial) from all species, whereas it contracted systemi...

Efficient cell electrotransfection can be achieved using combinations of high-voltage (HV; 800 V/cm, 100 micros) and low-voltage (LV; 80 V/cm, 100 ms) pulses. We have developed equipment allowing the generation of various HV and LV combinations with precise control of the lag between the HV and LV pulses. We injected luciferase-encoding DNA in skeletal muscle, before or after pulse delivery, an...

Purpose: It is unknown how use and outcome of laparoscopic liver resection (LLR) compare between high-volume centres (HV) low-medium volume (LMV). This study aimed to LLR according surgical difficulty in three leading European HV twenty Dutch LMV. Method: An international, retrospective multicentre cohort including data from LMV January 2011 December 2016. are defined by performing >50 annually...

Abstract Reconstructing a discrete object by means of X-rays along finite set U (discrete) directions represents one the main task in tomography. Indeed, it is an ill-posed inverse problem, since different structures exist having same projections all lines whose range . Characteristic ambiguous reconstructions are special configurations, called switching components, understanding issue tomograp...

This paper proposes a differential evolution with local information (DELI) algorithm for Takagi–Sugeno– Kang-type (TSK-type) neuro-fuzzy systems (NFSs) optimisation. The DELI algorithm uses a modified mutation operation that considers a neighbourhood relationship for each individual to maintain the diversity of the population and to increase the search capability. This paper also proposes an ad...

Background Lack of habituation of visual evoked potentials (VEP) is a common finding in migraine patients between attacks. Previous studies have suggested an electrophysiological familial aggregation pattern associated with migraine. The aim of this study was to evaluate the influence of a positive familial history of migraine on VEP amplitude and habituation. Methods We recorded six blocks of ...