OBJECTIVE To provide the empirical basis for using ocular vestibular evoked myogenic potentials (oVEMPS) in response to Fz bone conducted vibration (BCV) stimulation to indicate vestibular function in human subjects. To show the generality of the response by testing a large number of unselected healthy subjects across a wide age range and the repeatability of the response within subjects. To pr...

Copper plays essential roles in biology, but abnormal interactions are damaging. Reliable quantification of copper-protein interactions will underpin the molecular understanding of copper nutrition and toxicity. We have previously established two high affinity probes, Bathocuproine disulfonate (Bcs) and Bicinchoninate (Bca) anions, that are capable of in vitro quantification of Cu(i) binding wi...

An analysis is given and proposals are presented to improve the maintenance level in implementation of law 297-FZ, Art. 11 by improving testability suitability for diagnostics resource-determining nodes domestic energy-saturated equipment

The regulation of firing thresholds of cortical pyramidal cells has been suggested as one of the mechanisms underlying the generation of the P300 component of the human event-related potential. According to this hypothesis, the detection of an important stimulus produces a widespread inhibition of "irrelevant" networks, interrupting the ongoing cortical activity and facilitating the analysis of...

Cytokine antibody arrays were used to establish the profiles of cytokine release from THP-1 monocytes exposed to different amphotericin B (AMB) drug delivery systems. Fungizone (FZ) and Amphotec (ABCD) caused the release of significantly more inflammatory molecules and the release of inflammatory molecules at higher levels than either AmBisome (L-AMB) or Abelcet (ABLC) after 6 h of treatment. S...

The receptor tyrosine kinase (RTK) MuSK is part of the receptor complex that initiates neuromuscular junction formation in response to agrin [1–3]. MuSK, as well as the related orphan RTK-like proteins Ror1 and Ror2 [4], and their homologs in lower organisms, have an extracellular region composed of varying combinations of immunoglobulin and Kringle domains, but they all also have a domain defi...

steps during the development of multicellular eukaryotic organisms. As embryonic cells are incorporated into the blastoderm epithelia they begin to display the hallmark characteristics of apical–basal polarity, and during successive stages of development, cell polarity continues to play a significant role, influencing patterns of cell division, shape change and movement. Therefore, developmenta...

BACKGROUND Recent studies have revealed that the properties Traditional Chinese Medicine is mostly associated with are substance and energy metabolism. Our study aimed to compare the effect of red ginseng (RG) (warm property) and ginseng leaves (GL; cold property) on the substance and energy metabolism of rats with hypothyroidism. MATERIALS AND METHODS Rats were administered propylthiouracil ...

The 2016 Kumamoto earthquakes in Kyushu, Japan, started with a magnitude (M) 6.5 quake on April 14 on the Hinagu fault zone (FZ), followed by active seismicity including an M6.4 quake. Eventually, an M7.3 quake occurred on April 16 on the Futagawa FZ. We investigated if any sign indicative of the M7.3 quake could be found in the space–time changes in seismicity after the M6.5 quake. As a qualit...

INTRODUCTION Certain features of event-related potentials (ERPs), electroencephalographic (EEG), and behavioural measures vary with differing states of alertness and/or sedation. PURPOSE This study was conducted to investigate changes in several measures usually viewed as reflecting states of sedation/sleepiness associated with the use of a range of doses of the hypnotic benzodiazepine (BZD) ...