More than 390 million human dengue virus (DENV) infections occur each year, worldwide. Dengvaxia, a live-virus tetravalent vaccine from Sanofi Pasteur, was recently approved for clinical use, although performance against the four DENV serotypes is highly variable. Other vaccines in advanced testing also demonstrate variability efficacy. In this review, we outline benefits and challenges of deve...

Musical improvisation is driven mainly by the unconscious mind, engaging the dialogic imagination to reference the entire cultural heritage of an improvisor in a single flash. This paper introduces a case study of evolutionary computation techniques, in particular genetic coevolution, as applied to the frequency domain using MPEG7 techniques, in order to create an artificial agent that mediates...

Because cultivation of exotic woody ornamental plants has led to establishment of a number of invasive species, there is considerable interest in breeding methods to reduce the propensity for spread. We review progress in conventional breeding and transgenic biotechnology approaches to producing sterile forms of ornamental woody plants. Conventional forms of inducing sterility, including induct...