BACKGROUND Ethno-botanical information shows that Eremomastax speciosa is used in the traditional management of various stomach complaints including gastro-duodenal ulcers. MATERIALS AND METHODS In this study, we tested the cytoprotective potential of the whole plant methanol extract (100-200 mg/kg, p.o), against HCl/ethanol, absolute ethanol, cold/restraint stress rats, and pylorus legated r...

The conventional method used to study gastric secretion and activity involves the withdrawal and examination of specimens of gastric juice. Such a procedure subjects the average patient to considerable physical and emotional stresses. Further, the repeated collection of samples of gastric juice from a great number of individuals over a prolonged period of time presents many practical difficulti...

Ingestion of placenta or amniotic fluid by rats has been shown to enhance ongoing opioid-mediated antinociception, but does not, by itself, produce antinociception. This enhancement is produced by an active substance(s) in placenta and amniotic fluid that we have termed POEF for placental opioid-enhancing factor. Previous research has shown that enhancement requires mediation by the gastrointes...

The effect of taurine on gastric hemorrhage and mucosal erosion in the brain ischemia (BI) is unknown. The aim of the research was to study the involvement of gastric oxidative stress in hemorrhagic erosion produced in BI rats. The protective effect of taurine on this erosion model was evaluated. Male Wistar rats were deprived of food for 24 h. Under chloral hydrate -anesthesia, bilateral carot...

A model stomach system was used to investigate disintegration of various foods in simulated gastric environment. Food disintegration modes and typical disintegration profiles are summarized in this paper. Mechanisms contributing to the disintegration kinetics of different foods were investigated as related to acidity, temperature, and enzymatic effect on the texture and changes in microstructur...

Background: Ethno-botanical information shows that Eremomastax speciosa is used in the traditional management of various stomach complaints including gastro-duodenal ulcers. Materials and Methods: In this study, we tested the cytoprotective potential of the whole plant methanol extract (100-200 mg/kg, p.o), against HCl/ethanol, absolute ethanol, cold/restraint stress rats, and pylorus legated r...

Three dogs were surgically prepared with gastric fistulas and Heidenhain (vagally denervated) pouches. Acid and pepsin responses to pentagastrin and food were determined before, at the end of a 1-mo period of total parenteral feeding, and 1 mo after the resumption of a normal oral diet. Acid and pepsin output from the denervated pouch in response to pentagastrin and food decreased significantly...

BACKGROUND AND AIM Bronchiolitis obliterans (BO) is the main pulmonary involvement resulting from sulfur mustard (SM) gas exposure that was used against Iranian civilians and military forces during the Iran-Iraq war. The present study aimed to investigate the prevalence of gastro-esophageal reflux (GER) and gastric micro-aspiration in SM gas injured patients with chronic pulmonary diseases and ...

E SUCCESS of liver therapy in Addisonian pernicious anemia and the elucidation of the role of the stomach in blood formation are milestones of modern hematology. According to Castle’s hypothesis, normal gastric juice contains a special substance, intrinsic factor, produced by the gastric mucosa. This substance reacts with an extrinsic factor contained in the food. The production is an antianemi...

The present study was designed to determine whether the gastric freezing promotes the healing of peptic ulcer or not. Except for the control group, all the dogs were subjected to the gastric freezing and a standard experimental gastric ulcer was created afterwards at the varying intervals of 1, 3 and 6 months respectively. Control dogs were subjected to the ulcer operation only. Three weeks pos...