Gastric duplication cyst (GDC) with a pseudostratified columnar ciliated epithelium is an uncommon malformation supposed to originate from a respiratory diverticulum arising from the ventral foregut. Morphologic appearance of GDCs is variable, depending on the density of their contents. GDCs are often misdiagnosed as solid masses by imaging techniques, and as a consequence they may be wrongly o...

Despite advancements in therapy for advanced gastric and gastroesophageal junction cancers, their prognosis remains dismal. Tumor angiogenesis plays a key role in cancer growth and metastasis, and recent studies indicate that pharmacologic blockade of angiogenesis is a promising approach to therapy. In this systematic review, we summarize current literature on the clinical benefit of anti-angio...

We report a case of a male, aged 84, with type 2 diabetes, arterial hypertension, ischemic cardiomyopathy and chronic renal disease. We placed a percutaneous endoscopic gastrostomy one year ago, and we did not notice any injuries in the esophagus. We performed an urgent gastroscopy because the patient had an episode of coffee-ground vomit. In the distal third of the esophagus the mucosa had a n...

In recent years the incidence of gastroesophageal junction (GEJ) tumors has been rapidly increasing. Many trials have investigated the role of preoperative radiochemotherapy for this specific subgroup. In past, GEJ tumors were sometimes considered either esophageal or gastric cancer, due to their anatomical location. Purpose of this paper is to elucidate the benefit of radiotherapy in combinati...

Anastomotic leaks occur in up to 5% of patients who undergo bariatric surgical procedures [1]. Reoperation is associated with a high morbidity, and a mortality of up to 10% [2]. Therefore, endoscopic management should be considered in the first instance. We present a case of a gastric anastomotic leak that was successfully closed with a cardiac septal occluder device (Amplatzer; St. Jude Medica...

HYPOTHESIS Helicobacter pylori is not associated with gastroesophageal reflux disease and its complications, including adenocarcinoma of the esophagus and the gastroesophageal junction (GEJ). DESIGN Retrospective analysis. SETTING University tertiary referral center. PATIENTS Two hundred twenty-nine patients with symptoms suggestive of foregut disease underwent esophageal manometry, 24-ho...