Pancreatic adenocarcinoma is the most pervasive form of cancer with high mortality rates. Being obscure at early stages, non-specific symptoms and their onset only in late stages disease lead to detection III–IV on initial diagnistics. Gastrointestinal stromal tumor (GIST) an intramucosal gastrointestinal tract, which a derivate interstitial cells Cajal. The unicity presented clinical case rare...

we report two cases of a gastrointestinal stromal tumor (gist) synchronous and metachronous, respectively, with pancreatic adenocarcinoma. to our knowledge, this is the first report of a gist involved 3 years after a ductal pancreatic adenocarcinoma. data from the literature and our cases seem to suggest that incidental gist may occur synchronously and metachronously with other cancers more fre...

DOI: 10.1590/S1679-45082017AI3772 A 52-year-old asymptomatic patient underwent a followup endoscopy for Barrett’s esophagus. His exam showed a 1.5cm bulge in the gastric antrum (Figure 1A). The patient was referred for endoscopic ultrasound, which considered the lesion as a gastrointestinal stromal tumor (Figure 1B), but not a typical one, a computed tomography (CT) of the abdomen was, then, su...

Gastrointestinal stromal tumors (GIST) are defined as mesenchymal of the gastrointestinal tract expressing proto-oncogene protein CD 117. GIST is a rare tumor small bowel, which can be difficult to diagnose and has varied clinical outcome. Prognosis dependent on size mitotic count. Radical surgical excision (R0) treatment choice for resectable non-metastatic disease. Imatinib first-line therapy...

Spontaneous hepatic hemorrhage is a rare condition that may be caused by an underlying hepatic tumor, most commonly hepatocellular carcinoma or hepatic adenoma. A spontaneous rupture of a hepatic metastasis from a gastric gastrointestinal stromal tumor is also extremely rare, and the majority of affected patients present with hypovolemic shock or an acute abdomen. In this article, we report the...

BACKGROUND/AIMS Fascin is an actin-bundling protein that is important in cell motility. Fascin expression has been shown to have a potential role in tumor progression for some epithelial tumors. However, there are only a few studies related to its expression in mesenchymal tumors. We investigated fascin expression in gastrointestinal stromal tumors. METHODS Thirty gastrointestinal stromal tum...

Here we presented a 60-year-old Taiwanese man with advanced gastrointestinal stromal tumor. Disease progression was noted during imatinib treatment. Surgical resection was done and mutation analysis of KIT gene in all the resected tumors revealed deletion mutations of codons 558-565 in exon 11, whereas a missense mutation was also identified at codon 822 in exon 17 in one resected tumor. Patien...

desmoplastic ameloblastoma is a rare variant of ameloblastoma. up until now, less than 150 patients have been reported in the literature. we report a case of desmoplastic ameloblastoma in a 45-year-old female with a painless swelling in the left anterior maxillary region. fine needle aspiration yielded no fluid. periapical and panoramic radiographs as well as computer tomography scan showed a m...