نتایج جستجو برای: gbd

تعداد نتایج: 647  

Journal: :Archives of Iranian medicine 2017
Chante Karimkhani Robert P Dellavalle Seyed M Karimi Vafa Rahimi-Movaghar Farshad Pourmalek Aliasghar A Kiadaliri Mohammad Ali Sahraian Gholamreza Roshandel Seyed Mohammad Fereshtehnejad Mostafa Qorbani Amir Radfar Maryam S Farvid Hamid Asayesh Sadaf G Sepanlou Shirin Djalalinia Amir Kasaeian Jagdish Khubchandani Reza Malekzadeh Maziar Moradi-Lakeh Kristopher J Krohn Ali H Mokdad Theo Vos Mohsen Naghavi

BACKGROUND Iran and its neighboring countries represent four world regions with unique cultures and geography. Skin diseases span a wide diversity of etiologies including infectious, inflammatory, autoimmune, vascular, neurogenic, and oncologic. The Global Burden of Disease Study (GBD) 2015 measures the burden from skin diseases in 195 countries. METHODS Epidemiologic data were collected from...

Journal: :Neuroepidemiology 2015
Thomas Truelsen Lars-Henrik Krarup Helle K Iversen George A Mensah Valery L Feigin Luciano A Sposato Mohsen Naghavi

BACKGROUND Stroke mortality estimates in the Global Burden of Disease (GBD) study are based on routine mortality statistics and redistribution of ill-defined codes that cannot be a cause of death, the so-called 'garbage codes' (GCs). This study describes the contribution of these codes to stroke mortality estimates. METHODS All available mortality data were compiled and non-specific cause cod...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2014
G E Raskob P Angchaisuksiri A N Blanco H Buller A Gallus B J Hunt E M Hylek A Kakkar S V Konstantinides M McCumber Y Ozaki A Wendelboe J I Weitz

BACKGROUND Thrombosis is the common pathology underlying ischemic heart disease, ischemic stroke, and venous thromboembolism (VTE). The Global Burden of Disease Study 2010 (GBD 2010) documented that ischemic heart disease and stroke collectively caused 1 in 4 deaths worldwide. GBD 2010 did not report data for VTE as a cause of death and disability. OBJECTIVE To review the literature on the gl...

2014
Tony Blakely Nick Wilson Bill Kaye-Blake

Diet is the leading cause of health loss globally according to the Global Burden of Disease (GBD) 2010, contributing 10% of all health loss [1]. Requiring many assumptions, the GBD team also estimated that 300,000 (95% uncertainty interval: 212,000 to 404,000) deaths per year were attributable to diets high in sugar-sweetened beverages (SSBs) [1], or about 0.6% of all deaths globally per year. ...

2017
Wangxin Xiao Peishan Ning David C. Schwebel Guoqing Hu

In 2011, China implemented a more severe drunk-driving law. This study evaluated the effectiveness of the law on road traffic morbidity and mortality attributed to alcohol use. Data were from two open-access data sources, the Global Burden of Disease (GBD) 2015 update and police data. Poisson regression examined the significance of changes in morbidity and mortality. Large gaps in crude death e...

2017
Peter Hotez Serap Aksoy

This year PLOS Neglected Tropical Diseases (PLOS NTDs) celebrates its tenth anniversary following the publication of the first issue in 2007 [1]. When PLOS NTDs was founded, the framework of the neglected tropical diseases (NTDs) as an alternative to "other diseases" (as they were then referred to in the Millennium Development Goals) was just getting started-especially for Africa [2, 3]. In the...

Journal: :PLoS Neglected Tropical Diseases 2007
Claudia Stein Tanja Kuchenmüller Saskia Hendrickx Annette Prüss-Űstün Lara Wolfson Dirk Engels Jørgen Schlundt

The Global Burden of Disease (GBD) concept has been used by the World Health Organization (WHO) for its reporting on health information for nearly 10 years. The GBD approach results in a single summary measure of morbidity, disability, and mortality, the so-called disability-adjusted life year (DALY). To ensure transparency and objectivity in the derivation of health information, WHO has been u...

Journal: :Genetics 2002
Sandra N Garcia Lorraine Pillus

Silencing provides a critical means of repressing transcription through the assembly and modification of chromatin proteins. The NAD(+)-dependent deacetylation of histones by the Sir2p family of proteins lends mechanistic insight into how SIR2 contributes to silencing. Here we describe three locus-specific sir2 mutants that have a spectrum of silencing phenotypes in yeast. These mutants are dep...

2016
Jihyun Yoon In Hwan Oh Hyeyoung Seo Eun Jung Kim Young Hoon Gong Minsu Ock Dohee Lim Won Kyung Lee Ye Rin Lee Dongwoo Kim Min Woo Jo Hyesook Park Seok Jun Yoon

This study is part of a 5-year research project on the national burden of diseases, injuries, and risk factors in Korea. Using disability-adjusted life years (DALYs), a metric introduced by the 1990 Global Burden of Disease (GBD) project, we performed a comprehensive and detailed assessment of the magnitude and distribution of both fatal and non-fatal health problems in the Korean population. T...

Journal: :PLoS Neglected Tropical Diseases 2008
Charles H. King Anne-Marie Bertino

The disability-adjusted life year (DALY) initially appeared attractive as a health metric in the Global Burden of Disease (GBD) program, as it purports to be a comprehensive health assessment that encompassed premature mortality, morbidity, impairment, and disability. It was originally thought that the DALY would be useful in policy settings, reflecting normative valuations as a standardized un...

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