Broth cultures of hemolytic streptococci derived from patients are capable of rapidly liquefying normal human fibrin clot. The active fibrinolytic principle is also contained in sterile, cell-free filtrates of broth cultures. The degree of activity of filtrates parallels the activity of whole broth cultures sufficiently closely to indicate that large amounts of the fibrinolytic substance are fr...

By J. PHILIP SAVITSKY, M.D. C HANGES in platelet adhesivemiess have been noted during the course of many different clinical conditions.t4 Imicreased platelet adhesiveness has been correlated by some investigators with a predisposition to thromboembolic phemiomena and vascular disease,2 but other work has not confirmed this suiggestion.3 It has been show’mi that there is a very close relation be...