نتایج جستجو برای: gemistocytic glioblastomas
تعداد نتایج: 2385 فیلتر نتایج به سال:
Therapy of glioblastoma has been very problematic with disappointing results using multiple therapeutic approaches. In general, glioblastomas are considered radioresistant tumors with different radiation modalities failing to control them in the clinic. However a comprehensive and detailed analysis of the radiosensitivity of glioblastoma cells has not been performed. We now present such an anal...
Abstract Background TERT promoter (TERTp) mutations are a biological marker of glioblastoma; however, the prognostic significance TERTp mutational status is controversial. We evaluated this impact by retrospectively analyzing outcomes patients with isocitrate dehydrogenase (IDH)- and TERTp-wildtype glioblastomas. Methods Using custom next-generation sequencing, we analyzed 208 glioblastoma samp...
BACKGROUND/AIM Magnetic resonance imaging (MRI) is a key modality not only for lesion diagnosis, but also to evaluate the extension, type and grade of the tumor. Advanced MRI techniques provide physiologic information that complements the anatomic information available from conventional MRI. The aim of this study was to determine whether there is a correlation between apparent diffusion coeffic...
Abstract Background Glioblastomas are the most common and highly malignant primary brain tumors in adults with a median survival of 15 months even appropriate treatment. Extracranial metastases extremely rare due to poor prognosis not allowing sufficient time spread. We report an case extracranial metastasis supra-tentorial glioblastoma involving skin, subcutaneous muscular layers, periauricula...
INTRODUCTION Glioblastoma is the most common and the most malignant type of gliomas. Cerebral hemispheres are usual locations for gliomas. Isolated third ventricular presentation is very rare for glioblastomas. A new case of isolated third ventricular glioblastoma has been presented in this report. CASE DESCRIPTION A 36-year-old woman was admitted to outpatient clinic with headache, blurred v...
OBJECTIVE Several studies have analyzed a correlation between the apparent diffusion coefficient (ADC) derived from diffusion-weighted MRI and the tumor cellularity of corresponding histopathological specimens in brain tumors with inconclusive findings. Here, we compared a large dataset of ADC and cellularity values of stereotactic biopsies of glioblastoma patients using a new postprocessing ap...
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