conclusions: according to our results, it is likely that the increased frequency of the fcγriiib-na1/na2 genotype is associated with impaired immune responses against vl and its subsequent clearance from the patient. results: our results indicated that polymorphisms within the fcγriiib gene (that lead to the expression of the na1/na2 isoforms) are significantly associated with vl. the results d...

background: single nucleotide polymorphism in the interleukin28b (il28b) gene was recently shown to be associated with a significant increase in response to interferon-α and ribavirin treatment in patients with chronic hepatitis c. similarly, thyroid disease (td) occurring during treatment confer an improved sustained virologic response (svr). objectives: to determine the role of il28b genotype...

prevalence of coagulopathies (n=6010) including factor viii deficient (haemophilia a) individuals (n=3205) were investigated and analysed in 24 provinces of iran. for all coagulopathies, the prevalence (per 100,000) was the highest with 24.45 in semnan (north east of iran), followed by hamadan (west) with 17.56, the lowest was observed in kordestan (west) as 0.88, followed by kohkiluyeh & boyr-...

cataract is multi-factorial eye disease identified by the disturbance of the transparent ocular lens. there is significant evidence suggesting oxidative damage as a major cause of initiation and progression of numerous diseases including cataracts. nad(p)h:quinone oxidoreductase 1 (nqo1; omim: 125860) and catalase (cat, omim: 115500) are antioxidant enzymes that prevent cells from oxidative str...

the study of genetic variation and phylogenetic relationships is essential for the efficient selection of superior plant material and conducting introgression breeding programs. in iran, despite the wide geographical distribution of grasses no report is available on the genetic diversity and relationships of cool season grass populations. in this study amplified fragment length polymorphism (af...

introduction: genetic resources in any country are valuable materials which needed to be conserved for a sustainable agriculture. an animal phenotype is generally affected by genetic and environmental factors. to increase mean performance in a population under consideration not only environmental conditions, but also genetic potential of the animals should be improved. although, environmental i...

olive cultivars with specific characteristics have been developed thanks to iran’s particular climatic conditionsand long-term olive cultivation. the genetic variation and relationships among 40 olive cultivars, as well as 17 unknown genotypes from the national olive collection orchard at tarom research station, zanjan, iran, were evaluated using ssr markers. using 10 microsatellite primer pair...

study of genetic relationships is a prerequisite for plant breeding activities as well as for conservation of genetic resources. since the hybrid canola have more yield than inbred lines, determine the genetic diversity of this have particular importance. in the present study, genetic diversity among 36 genotype of brassica sp. were determined using inter simple sequence repeat (issr) markers. ...

genetic trend for production traits were estimated in iranian holstein cattle using the first lactation data recorded by cattle breeding and dairy product improvement center of the state from 1991 to 2006. effect of some factors on genetic trend was investigated using data from 18 large herds. (co) variance components and genetic parameters were estimated, using five trait animal model and em-a...

anxiety comprises many clinical descriptions and phenotypes. a genetic predisposition to anxiety is undoubted; however, the nature and extent of that contribution is still unclear. extensive genetic studies of the serotonin (5-hydroxytryptamine, 5-ht) transporter (5-htt) gene have revealed how variation in gene expression can be correlated with anxiety phenotypes. complete genome-wide linkage s...