We studied the effect of single nucleotide polymorphisms (SNPs) on transgenerational inheritance of yeast segregants that were derived from a cross between a laboratory strain and a wild strain of Saccharomyces cerevisiae. We compared segregants with high minor allele content (MAC) relative to those with less and found a more dramatic shortening of the lag phase length for the high MAC group in...

genetic analysis of growth traits including body weight recorded at birth (bwt), 3 (3bwt), 6 (6bwt), 9 (9bwt) and 12 (12bwt) months of age was carried out using 4107 records on raieni cashmere goats born from 206 sires and 1402 dams, during years 1992 to 2006. the records were collected from a resource flock in baft research station, situated in kerman province, iran. the importance of addition...

asian citrus psyllid, diaphorina citri kuwayama, is an important pest of citrus that transmits the bacterial pathogens responsible for citrus greening disease, also called huanglongbing. the aim of the current study was to investigate the shape variations of the forewing among the iranian geographic populations of d. citri, as well as one population from pakistan. the adult psyllids used in thi...

The TCS-08, ITOP, and PREDICT field programs provided a rich set of data including Eldora radar data (TCS-08) and dropsondes (all projects) from a variety of platforms. We have analyzed the data from all three of these projects, focusing on the production of the three-dimensional variational analyses (3D-VAR) of winds and thermodynamic data for all potential cyclogenesis cases. From these analy...

The way people cope with stressors of day to day living has an important influence on health. The aim of the present study was to explore whether genetic and environmental variations in stress-coping differ over time during adulthood. The brief COPE was mailed to a large sample of the UK female twins (N = 4,736) having a wide range of age (20-87 years). Factor analyses of the items of the brief...

age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...

BACKGROUND Noise-induced hearing loss (NIHL) is a complex disease caused by environmental and genetic risk factors. This study explored the relationship between the genetic variations in the CASP gene and the risk of developing NIHL among Chinese workers exposed to occupational noise. METHODS A case-control study of 272 NIHL workers and 272 normal-hearing workers matched for age, sex and year...

Family studies have revealed that individual variations in the levels and structures of lipoproteins in the blood are due in large part to hereditary influences. Since such lipoprotein variations are strongly associated with atherosclerosis, the major cause of heart disease and stroke, the characterization of these hereditary influences provides an opportunity to better understand the genetic c...

If it were not for the great variability among individuals medicine might as well be a science and not an art.” The thoughts of Sir William Osler in 1892 reflect the view of medicine over the past 100 years.1 Modern pharmacogenetics has its origins in the 1950s with a series of discoveries.2 The genetic basis underlying variations in drug response has become evident with the introduction of mod...