Earlier we found a human hypervariable genomic region (GVR). The DNA hybridization probe isolated from this region detects multiple hypervariability of restriction DNA fragments from genomic loci. The sequencing data suggest that the genomic instability and variability are associated with tandem DNA repeats. The DNA hybridization probe contains two families of simple DNA repeats designated as '...

this study investigated the genetic diversity of morchella species using randomly amplified polymorphic dna markers. morchella species are an important group of edible mushrooms belonging to the family helveliaceae with medicinal and economical significance. in this study we have developed an efficient method of genomic dna isolation which was amplified by eight rapd primers to test the polymor...

The main objective of the present study was to develop an efficient and reliable probe to be routinely used for detection of chromosome 13 copy numbers by interphase FISH. To achieve this, a Yeast Artificial Chromosome (YAC) containing sequences specific for human 13q12 (744D11), was cultured and the whole yeast genomic DNA was extracted. The human insert within the isolated DNA was amplified b...