OBJECTIVE The PREDG trial was designed to study the influence of an educative program on gestational weight gain in women with pregestational obesity. METHODS Randomized controlled clinical (https://www.isrctn.com/ISRCTN61793947) 169 obesity (BMI ≥30 kg/m2). Women were randomized participate a group education nutrition and physical activity or conventional follow-up specialized Unit Obesity Pre...

The purpose of this series is to report the initial ECMO experience of the Neonatal Intensive Care Unit of Hospital de São João. The first three clinical cases are reported. Case report 1: a 39 weeks gestational age girl with severe lung hypoplasia secondary to a bilateral congenital diaphragmatic hernia. Case report 2: a 39 weeks gestational age girl with a right congenital diaphragmatic herni...

Women at ‘low risk’ of pre-eclampsia are most commonly those from unselected obstetric populations and may be nulliparous or multiparous. (Please see Appendix 6.1 for details of individual randomised controlled trials or systematic reviews of randomised controlled trials that reported on the outcomes of pre-eclampsia, gestational hypertension, maternal morbidity, small-for-gestational-age (SGA)...

background and objective: hypertensive disorders complicating pregnancy are common and from one of the deadly triad, along with hemorrhage and infection that contribute greatly to prenatal and maternal morbidity and mortality in the developing countries. this study was designed to investigate the relationship between maternal hypothyroidism and pre-eclampsia. materials and methods: in a prospec...

Hypertension complicates 6-8% of pregnancies and includes the following four conditions: hypertension preceding pregnancy or documented before the 20th week of gestation; pre-eclampsia (PE)/eclampsia; chronic hypertension with superimposed pre-eclampsia; and gestational hypertension. The latter is defined as a significant rise in blood pressure after the 20th week of pregnancy in previously nor...

Background: Involvement of the ocular system in pregnancy is a common finding females having PIH (pregnancy-induced hypertension). Aim: To judge association between pregnancy-induced hypertension changes fundus and fetal outcomes. Methods: In 306 pregnant with confirmed diagnosis hypertension, were assessed along The outcomes included neonatal death, stillbirth, 1-minute Apgar scores, birth wei...

To the Editor: Preeclampsia is a leading cause of maternal and fetal morbidity and mortality worldwide. It occurs in two phases: abnormal implantation of the placenta leads to impaired placental blood flow, which in turn induces the release of a critical placental substance into the maternal circulation (1 ). Clinical onset usually occurs in the third trimester of pregnancy, long after initiati...

INTRODUCTION This article is part of the Focus Theme of Methods of Information in Medicine on "Biosignal Interpretation: Advanced Methods for Studying Cardiovascular and Respiratory Systems". BACKGROUND Hypertensive pregnancy disorders affect 6 - 8 percent of all pregnancies and can result in severe complications for both the mother and the fetus. OBJECTIVES The aim of this study was to imp...

AIMS To evaluate the effects of gestational diabetes and pre-existing diabetes on maternal morbidity and medical costs, using data from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service. METHODS Delivery cases in 2010, 2011 and 2012 (459 842, 442 225 and 380 431 deliveries) were extracted from the Health Insurance Review and Assessment S...