BACKGROUND Myeloperoxidase (MPO) is an endogenous oxidant enzyme that produces reactive oxygen species (ROS) and may be involved in lung carcinogenesis. The MPO-463G>A polymorphism influences MPO transcription and has been associated with lung cancer susceptibility. However, the association between the MPO-463G>A polymorphism and lung cancer risk remains controversial. METHOD To investigate t...

UNLABELLED Systemic sclerosis (SSc) is a rare, autoimmune disease characterized by cutaneous and visceral fibrosis. Interleukin- 6 (IL-6) is involved in the pathogenesis of many immune-mediated diseases. IL-6 plays an important role in the initiation and promotion of fibrosis. The polymorphism in the position -174 (G/C) of the promoter region of the IL-6 gene (IL-6pr) may alter the expression o...

In transform image coding, the histograms of transform coeecients can be approximately modeled by generalized Gaussian (GG) random variables. However, the GG models may not t the DC distribution. One approach uses DPCM for the DC data, which greatly complicates bit allocation; another assumes a single Gaussian (SG) model, which may be a poor model. As an alternative, this paper proposes a nite ...

In the 21st century, teaching and learning mathematics courses witness significant expansion development of technology use, which creates a shift from teacher-centred to student-centred engagement. Student engagement (SE) faces many challenges poor performance student difficulty in solving simultaneous equations involving indices (SEII), among others. This paper presents an evaluation viewpoint...

The DMA (DM ? chain) gene, a member of non-classical MHC class II plays an important role in the process presenting antigen peptides by producing DM protein. This study aimed to identify polymorphism gene and their associations with disease resistance traits such as total IgY concentration ND antibody titers IPB-D2 chicken line. sample used was 101 chickens consisted 81 G0 (53 female 28 male) 2...

X-ray cross-complementing group 4 (XRCC4) is crucial for cells to maintain genetic stability thereby inflicting carcinogenesis. To date, epidemiologic findings have reached conflicting and ambiguous conclusions on the role of XRCC4 rs1805377 polymorphism in cancer risks. We made a comprehensive quantitative evaluation by performing a meta-analysis. Eligible publications assessing the associatio...

PURPOSE To investigate the association of C5 SNPs with proliferative diabetic retinopathy (PDR) of type 2 diabetes (T2D). METHODS A total of four C5 SNPs including rs2269067, rs7040033, rs1017119 and rs7027797 were genotyped in 400 PDR patients with T2D (cases) and 600 non- proliferative diabetic retinopathy PDR (NPDR) with T2D patients (controls) by using PCR-RFLP method. mRNA expression was...

The relationship between vascular endothelial growth factor gene polymorphism and gastric cancer risk and its development, prognosis, and survival are still being debated. This meta-analysis was performed to assess these relationships. The association reports were identified from PubMed, Embase, Cochrane Library, and CBM-disc (China Biological Medicine Database), and eligible studies were inclu...

Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are ubiquitous viruses belonging to the Herpes viridae family, which consists of over 100 known viruses infecting organisms from oysters to humans. HSV-1 and HSV-2 often lead to asymptomatic infections in humans, nevertheless different clinical presentations can be seen including recurring oral and genital lesions, meningitis and less commo...