The dedifferentiated giant-cell tumor of the bone is a very rare variant of the giant-cell tumor (GCT). We report the clinical, radiographic and histological findings of a dedifferentiated GCT in which the dedifferentiated component consisted of small round cells. We also comment on previously reported cases of dedifferentiated GCT, discuss the clinical implications of this dual histology, and ...

A giant cell tumor (GCT) is an osteolytic tumor occurring in young adults at the epiphysis or end of the long bone. This occurs after the epiphyseal plate has ossified and longitudinal bone growth is completed. Giant cell tumor is one of the most obscure and intensively examined tumours of bone. Its histogenesis is uncertain, the histology does not predict the clinical outcome and there are sti...

Giant cell tumor of the tendon sheath is a tumor, which affects mainly hands people aged 30 to 50 years with female prevalence. Magnetic resonance imaging (MRI) essential for diagnosis and treatment planning. The aim this study evaluate efficacy multiecho gradient-echoes (MeGE) sequence in detecting hemosiderin hallmark tumor. MRIs were performed sample 11 patients mean age 45. With proposed pr...

cancer stem cells (csc) are the tumor-associated cells existed within tumors or hematological cancers which share characteristics similar to normal stem cells. the common characteristics of a normal stem cell and a csc are their differentiation capacity and self-renewal in tumors. the expression pattern of csc markers differs depending on the type and location of cancers. cd molecules are proba...

Giant-cell tumor of bone is a rare, locally aggressive tumor that typically occurs in the bones of skeletally mature young adults in their second to fourth decades. Traditionally, surgery has been the mainstay of therapy for this disease, but the disease can recur even with optimal procedures. Furthermore, it may occur in locations where a surgical approach would be morbid. The maturation of th...

The congenital epulis is a benign congenital granular cell tumor arising most often of the alveolar ridge of the jawbone. When giant, it is source of digestive discomfort disabling feeding. We report the case of a newborn female, vaginal delivery, presented with a giant intraoral tumor. Tumor obstructing the mouth of the newborn and prevent the attachment and feeding. The treatment consisted of...

OBJECTIVES We aimed to determine the demographic characteristics of giant cell tumor around the knee in China. METHODS Between March 2000 and June 2014, patients with primary giant cell tumor around the knee were recruited from 6 institutions located in different regions of China, and were reviewed retrospectively the clinical features according to gender and age. RESULTS 334 qualified pati...

Objective: To study the clinical and pathological features of giant cell angioblastoma in children. Method: The clinical and pathological data of 3 pediatric cases of giant cell angioblastoma were retrieved and reviewed from the medical records in Children’s Hospital of Fudan University. Histological and immunohistochemical analysis was made. Results: There were 2 boys and 1 girls. The age was ...

A 60-year-old male presented with dyspnea and chest pain. He was referred with massive bulky mass. A mass in the left lung was observed using chest X-ray (Figures 1).  A computed tomography scan of the chest showed a mass on the left lung with complete lung collapse Figures 2 (A, B). The needle biopsy was performed and the case was diagnosed with solitary fibro...