نتایج جستجو برای: ginkgolide b

تعداد نتایج: 899403  

2011
Andrew J. Thompson Gavin E. Jarvis Rujee K. Duke Graham A.R. Johnston Sarah C.R. Lummis

Extracts from the Ginkgo biloba tree are widely used as herbal medicines, and include bilobalide (BB) and ginkgolides A and B (GA and GB). Here we examine their effects on human 5-HT(3)A and 5-HT(3)AB receptors, and compare these to the effects of the structurally related compounds picrotin (PTN) and picrotoxinin (PXN), the two components of picrotoxin (PTX), a known channel blocker of 5-HT(3),...

Journal: :Current drug targets 2000
F V DeFeudis K Drieu

The effects of EGb 761 on the CNS underlie one of its major therapeutic indications; i.e., individuals suffering from deteriorating cerebral mechanisms related to age-associated impairments of memory, attention and other cognitive functions. EGb 761 is currently used as symptomatic treatment for cerebral insufficiency that occurs during normal ageing or which may be due to degenerative dementia...

2008
Margarita Aponte Wei Jiang Montaha Lakkis Ming-Jiang Li Dale Edwards Lina Albitar Allison Vitonis Samuel C. Mok Daniel W. Cramer Bin Ye

Among the proinflammatory mediators, platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a major primary and secondary messenger involved in intracellular and extracellular communication. Evidence suggests that PAF plays a significant role in oncogenic transformation, tumor growth, angiogenesis, and metastasis. However, PAF, with its receptor (PAFR) and their ...

Journal: :Cancer research 2008
Margarita Aponte Wei Jiang Montaha Lakkis Ming-Jiang Li Dale Edwards Lina Albitar Allison Vitonis Samuel C Mok Daniel W Cramer Bin Ye

Among the proinflammatory mediators, platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a major primary and secondary messenger involved in intracellular and extracellular communication. Evidence suggests that PAF plays a significant role in oncogenic transformation, tumor growth, angiogenesis, and metastasis. However, PAF, with its receptor (PAFR) and their ...

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