objective: glioblastoma multiforme (gbm), one of the most common and aggressive malignant brain tumors, is highly resistant to radiotherapy. numerous approaches have been pursued to find new radiosensitizers. we used a picogreen and colonogenic assay to appraise the dna damage and cell death in a spheroid culture of gbm cells caused by iodine-131 (i-131) beta radiation in the presence of topote...

Glioblastoma is most common and most aggressive cancer of brain. for treatment surgery is first selection and radiation therapy then chemotherapy. The median survival of Patients with GBM is less than a year after diagnosis. Glioblastoma is basically resistant to common cancer treatments. today to improve the response of patients to treatment, a number of strategies such as the use of radiation...

Tonglu rhythmites (Upper Ordovician) in Zhejiang Province, east-central China, display three orders of cyclicity in sandstone and mudstone layer thickness. Millimeter-thick alternations of sandstone and mudstone laminae are ascribed to single tidal cycles. Centimeter-thick alternations of sand-dominated layers (SDLs) and muddominated layers (MDLs) are interpreted to be related to alternation of...

Cohen class time–frequency distributions serve as alternatives to the traditional spectrogram and are known for their ability to provide simultaneous resolution in time and frequency. They employ a kernel along with the signal’s Wigner distribution. Kernel design has witnessed significant attention. Very recently Costa and BoudreauxBartels have proposed a multiform tiltable exponential distribu...

Erythema nodosum leprosum is characterised by brightly erythematous tender nodules or plaques usually in bilateral symmetrical distribution. ENL can also present in several atypical presentations like pustular, erythema multiform like, ulcerative, necrotic, panniculitic and bullous forms. Various precipitating factors for ENL include stress, pregnancy, surgery, lactation, menstruation, infectio...

Glioblastoma is one of the most common primary brain tumors (80% of patients) that has a poor prognosis due to malignancy. Glioblastoma has an annual incidence of 5.26 per 100 000 population or 17 000 new diagnoses per year and so as the population aging, the number of patients is expected to increase. There is a growing body of literature investigating the tumor microenvironmenta...