The findings on electrophoretic analysis of plasma proteins during many weeks of low protein feeding in dogs accord in general with those of chemical analysis as concerns the alterations in plasma albumin and globulin concentrations. Long continued restriction of dietary protein results in decreased albumin levels while plasma globulin concentrations remain essentially normal. The degree of dep...

The article presents the results of dynamics indicators protein, nitrogen and carbohydrate metabolism during castration boars in industrial production against background immunocorrection with thymogen. studies were carried out on 14 (aged 5 months), selected by random sampling from 38 animals compliance principle paired analogues divided into two groups ‒ control experimental ones (n=7 each). A...

Fluorescein-labelled aggregated human gamma-globulin was found to react in precipitin-type tests with serums of individuals with rheumatoid arthritis. This reagent was also highly reactive and specific for the localization of rheumatoid factor in frozen sections of synovial membranes, lymph nodes, and subcutaneous nodules. In synovial membranes from patients with active rheumatoid arthritis, rh...

Testosterone-estradiol-binding globulin in human plasma was characterized and quantified by polyacrylamide gel electrophoresis. Testosterone and estradiol were shown to bind to a single homogeneous protein over a wide range of experimental conditions. Testosterone binding to cortisolbinding globulin (transcortin) and estradiol binding to albumin were clearly demonstrated; both transcortin and a...

Deficiency of alpha1-antitrypsin (AAT) is a common but underdiagnosed genetic disorder. Severe AAT deficiency may be detected by the absence of alpha1-globulin protein fraction by serum protein electrophoresis (SPEP). Routine SPEP may represent an underused resource for the identification of AAT deficiency. Total alpha1-globulin protein was measured in 47 MM, 24 MZ, and 19 ZZ phenotype serum sa...

Holmberg and Laurell (1948) gave the name " caeruloplasmin " to a blue copper globulin complex which they had isolated from both pig and human blood (1947). It was obtained by ammonium sulphate precipitation and was found to be active as an oxidase against p-phenylenediamine. Tlhey considered it to be an a globulin with a molecular weight of about 150,000. Other workers (Scheinberg and Gitlin, ...

The cleavage into large fragments of both normal and immune rabbit y-globulin by cysteine-activated papain was reported by Porter (1, 2). In the case of immune y-globulin the antibody activity was found associated with two of the three principal fragments isolated. Nisonoff et al. (3) have carried out the cleavage of rabbit immune y-globulin into similar fragments with a sedimentation constant ...

BACKGROUND Basiliximab and anti-thymocyte globulin are widely used drugs for induction therapy after pediatric heart transplantation. The aim of this study was to determine whether any differences could be observed between basiliximab and anti-thymocyte globulin, with respect to long-term mortality, in a population of pediatric cardiac transplant recipients. METHODS AND RESULTS An analysis of...