نتایج جستجو برای: glomerular basement membrane

تعداد نتایج: 417463  

2011
Brooke M. Steenhard Adrian Zelenchuk Larysa Stroganova Kathryn Isom Patricia L. St. John Glen K. Andrews Kenneth R. Peterson Dale R. Abrahamson

Laminin α5 is required for kidney glomerular basement membrane (GBM) assembly, and mice with targeted deletions of the Lama5 gene fail to form glomeruli. As a tool to begin to understand factors regulating the expression of the LAMA5 gene, we generated transgenic mice carrying the human LAMA5 locus in a bacterial artificial chromosome. These mice deposited human laminin α5 protein into basement...

Journal: :The Journal of clinical investigation 1978
B A Bray

Cold-insoluble globulin (CIG), which is immunochemically indistinguishable from the fibroblast surface protein known as large external transformation-sensitive glycoprotein and fibronectin, was detected immunologically in connective tissue fractions from adult human lung. The fractions tested were (a) intact parenchyma, (b) acidic structural glycoproteins (ASG) extracted from lung parenchyma wi...

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