نتایج جستجو برای: gnrha long protocol

تعداد نتایج: 1006411  

Journal: :Human reproduction 1995
E Shalev Y Geslevich M Matilsky M Ben-Ami

The clinical outcome of intrauterine insemination (IUI) treatment cycles employing a gonadotrophin-releasing hormone agonist [GnRHa, triptorelin (Decapeptyl)] or human chorionic gonadotrophin (HCG) for ovulation induction was compared. A group of 48 patients presenting with amenorrhoea, oligomenorrhoea or unexplained infertility were all treated with human menopausal gonadotrophins (HMG) from d...

Journal: :The Kurume medical journal 2007
Go Matsuo Kimio Ushijima Atsuhiko Shinagawa Syun-Ichi Takahashi Naoki Fujiyoshi Syuji Takemoto Atsumu Terada Akimasa Fukui Toshiharu Kamura

To reduce chemotherapy induced gonadotoxicity, co-treatment with gonadotropin releasing hormone against analogue (GnRHa) was tested using rat model. Leuprorelin acetate (Leuplin) with or without cisplatin (CDDP) was given subcutaneously at a dose of 9.4 microg/ml to Wistar strain female rats. The total number of follicles was counted and the maturation of follicles was evaluated at the largest ...

2015
Qing Li Peter Szatmary Yanyang Liu Zhenyu Ding Jin Zhou Yi Sun Feng Luo Yan Wang Jiang Zhu

Therapy advances are constantly improving survival rates of cancer patients, however the toxic effects of chemotherapy drugs can seriously affect patients' quality of life. In women, fertility and premature ovarian endocrine dysfunction are of particular concern. It is urgently we find methods to preserve or reconstruct ovarian function for these women. This study compares GnRHa treatment with ...

2015
H. Nur Peltek Kendirci Sebahat Yılmaz Ağladıoğlu Veysel N. Baş Aşan Önder Semra Çetinkaya Zehra Aycan

Objective. GnRH analogues (GnRHa) are used in the treatment of central precocious puberty (CPP). The purpose of this study was to evaluate the efficacy of treatment with a GnRHa (leuprolide acetate) in patients with CPP. Subjects and Methods. A total of 62 female child patients who had been diagnosed with CPP, rapidly progressive precocious puberty (RP-PP), or advanced puberty (AP) and started ...

Journal: :Endocrinology 1999
N Atanassova C McKinnell M Walker K J Turner J S Fisher M Morley M R Millar N P Groome R M Sharpe

This study aimed to identify the mechanism(s) for impairment of spermatogenesis in adulthood in rats treated neonatally with estrogens. Rats were treated (days 2-12) with 10, 1, or 0.1 microg diethylstilbestrol (DES), 10 microg ethinyl estradiol (EE), 10 mg/kg of a GnRH antagonist (GnRHa), or vehicle and killed in adulthood. DES/EE caused dose-dependent reductions in testis weight, total germ c...

Journal: :Molecular human reproduction 1997
Q Dou R W Tarnuzzer R S Williams G S Schultz N Chegini

Tissue remodelling involving extracellular matrix (ECM) turnover plays a major role in leiomyoma growth and regression, regulated by the combined action of matrix metalloproteinases (MMPs) and the tissue inhibitors of MMPs (TIMPs). We postulated that leiomyomata express MMP and TIMP mRNA and protein, and their expression is inversely regulated during tumour growth and gonadotrophin releasing ho...

1996
Ekaterini Chatzaki Christopher M. R. Bax Karin A. Eidne Lorraine Anderson J. Gedis Grudzinskas Christopher J. Gallagher

The presence of a direct extra-pituitary action of gonadotropin-releasing hormone (GnRH) via specific receptors in endometrial cancer (EC) has been suggested as an explanation for the therapeutic effect of GnRH analogue (GnRHa) in recurrent disease. We have sought the expression of the GnRH peptide and functional GnRH receptor (GnRH-R) in human tissues and cell lines to investigate the possibil...

2017
Hye Ryun Kim Hyo-Kyoung Nam Young-Jun Rhie Kee-Hyoung Lee

PURPOSE This study investigated the influence of obesity on the clinical course and effect of gonadotropin-releasing hormone analog (GnRHa) treatment in girls with central precocious puberty (CPP). METHODS Medical records of 182 girls with CPP treated with GnRHa were reviewed. They were divided into 2 groups: normal weight (n=108) and overweight/obesity (n=74). Chronological age (CA), bone ag...

Journal: :BJOG : an international journal of obstetrics and gynaecology 2002
Malini Sharma Lucie Buck George Mastrogamvrakis Konstantinos Kontos Adam Magos Alex Taylor

OBJECTIVE To conduct a cost effectiveness analysis of pre-operative gonadotrophin releasing hormone agonists (GnRHa) in women with uterine fibroids undergoing hysterectomy or myomectomy. DESIGN A cost effectiveness analysis using the effectiveness data from a systematic review of GnRHa. SETTING Secondary care. SAMPLE Women with uterine fibroids undergoing hysterectomy or myomectomy and wo...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید