The ovo and ovarian tumor genes are required during early and late stages of Drosophila oogenesis. The ovo product, a zinc-finger transcription factor, can bind to sites and influence the level of expression of the ovarian tumor promoter. Our examination of ovo null mutant organelles demonstrate that it is required for the differentiation of XX germ cells during larval gonial stages, in additio...

The aims of the study were to identify craniofacial characteristics in patients with the rough hypoplastic amelogenesis imperfecta (AI) phenotype and to evaluate whether craniofacial variables are related to a mutation in either of the two genes associated with AI, enamelin (ENAM) and amelogenin (AMGX). Eight children (five males and three females) with rough hypoplastic AI phenotype, aged 6.5-...

Nine monoand di-chloro-s-triazine (Procion) dyes (Table) have been tested for possible use as vital markers in rhesus monkeys (Macaca mulatta). Goland and Grand (Am J Phys Anthropol 29:201-218, 1968), Prescott, Mitchell, and Fahmy (Am J Phys Anthropol 29:219-224, 1968), and Seiton and Engel (Am J Anat 126: 373-391, 1969) have demonstrated that certain types of reactive dyes are preserved in dec...

The fate of stem cells is intricately regulated by numerous extrinsic and intrinsic factors that promote maintenance or differentiation. The RNA-binding translational repressor Pumilio (Pum) in conjunction with Nanos (Nos) is required for self-renewal, whereas Bam (bag-of-marbles) and Bgcn (benign gonial cell neoplasm) promote differentiation of germ line stem cells in the Drosophila ovary. Gen...

The use of genetically modified mice can accelerate progress in auditory research. However, the fundamental profile of mouse hearing has not been thoroughly documented. In the current study, we explored mouse middle ear transmission by measuring sound-evoked vibrations at several key points along the ossicular chain using a laser-Doppler vibrometer. Observations were made through an opening in ...

OBJECTIVES The impaction of the second mandibular molar (MM2) has recently become more prevalent. Several etiological hypothesis have been proposed to investigate the association between skeletal features and impaction of MM2. The aims of this study were to analyze the skeletal features in patients with MM2 impaction and the association between arrested eruption of MM2 and the presence of the t...

Although there have been some reports on the relationship between craniofacial morphology and the activity of the temporal muscle attached to the coronoid process, such relationship is still unclear. The aim of the present study was therefore to investigate the relationship between the coronoid process and overall craniofacial morphology using lateral cephalograms of 60 female subjects (mean ag...