We present the case of a previously healthy 59-year-old man who was under treatment for scleritis and episcleritis when he developed a parotid-gland swelling and pus-producing sinus. On surgical exploration, the features were those of a parotid abscess, but the lesion not only failed to heal post-operatively but increased in size very significantly. There was also severe necrotizing keratitis o...

Oral vegetable granuloma represents an inflammatory lesion of foreign body origin resulting from the implantation of vegetable matter. Controversy regarding its pathogenesis is reflected by the various terminologies used to describe the lesion. Its diverse clinical presentations are due to variations in the antigenic potential of the vegetable material and the host response. As the diagnosis is...

This paper describes one patient with Antineutrophil Cytoplasmic Antibody- (ANCA-) associated vasculitis who initially presented with multiple ischemic fingers and toes. On further evaluation, the patient was also found to have pulmonary-renal involvement and episcleritis. The diagnosis was supported with a positive cANCA (anti-proteinase 3) and a bronchoscopy consistent with diffuse alveolar h...

Relevance. Granulomatosis with polyangiitis (Wegener's granulomatosis) is a rare disease in which oral cavity symptoms manifest as 'strawberry' gingivitis. Description of the clinical case. The paper presents early systemic – granulomatosis manifestation gingival hyperplasia 1 patient, form so-called "strawberry gingivitis", another non-specific ulcer on mucous mem-brane soft palate. After exam...

Granulomatosis with polyangiitis (GPA), known as Wegener’s granulomatosis, is characterized by systemic necrotizing vasculitis in small and medium sized vessels affecting the upper and lower respiratory tracts, paranasal sinuses, and kidneys (1). We here describe a patient who presented with acute congestive heart failure (CHF) and progressive renal failure requiring hemodialysis and was later ...

Objective: To determine the clinical and laboratory features during disease course in patients of anticytoplasmic antibody (ANCA) associated vasculitis Pakistani presenting to a tertiary care center.
 Study Design: Case series.
 Place Duration Study: Fatima Memorial Hospital Shadman Lahore, from Dec 2018 Mar 2019.
 Methodology: A collection 20 regarding demographic data, constitu...

Eosinophilic granulomatosis with polyangiitis formerly named “Churg-Strauss syndrome (CSS)” is a systemic disease with bronchial asthma, hypereosinophilia, and systemic vasculitis. We report a case of CSS with cholecystitis and mononeuritis multiplex. A 50-year-old woman with a history of sinusitis and bronchial asthma of 8 years’ duration was referred with a complaint of left-hand deformity an...

The granulomatosis with polyangiitis, initially known as Wegener's granulomatosis, is a small and medium vessels vasculitis. It's classic form presents a triad: necrotizing granuloma of respiratory tract, necrotizing cutaneous vasculitis and glomerulonephritis. This vasculitis has cytoplasmic antineutrophil antibodies as signal. This work illustrates a case, of multisystemic rare disease, in wh...

Background: Wegener granulomatosis or granulomatosis with polyangiitis is a pauci-immune small vessel vasculitis which is usually associated with anti-neutrophil cytoplasmic antibodies (ANCA) mainly in old men. This small vessel vasculitis is usually characterized by necrotizing granulomatous inflammation with multiorgan involvement. Kidneys could be involved as the main and life-threatening co...

1 Van Vooren JP, Turneer M, Yernault JC, Dc Bruyn J, Burton E, Legros F, Farber CM. A multidot finmunobinding assay for the serodiagnosis oftuberculosis. Comparison with ELISA technique. J Immunol Methods 1988; 113:45-49 2 Van %boren JP, Farber CM, Motte 5, De Bruyn J, Legros F, Yernault JC. Assay of specific antibody response to myobacterial antigen for the diagnosis of a pleural effusion in a...