The small scaffold protein PED/PEA-15 is involved in several different physiologic and pathologic processes, such as cell proliferation and survival, diabetes and cancer. PED/PEA-15 exerts an anti-apoptotic function due to its ability to interfere with both extrinsic and intrinsic apoptotic pathways in different cell types. Recent evidence shows that mice overexpressing PED/PEA-15 present large...

in this study, total factor productivity growth of iran’s pulses (including irrigated pea, dry pea, irrigated lentil, dry lentil, irrigated soybean, dry soybean and irrigated bean) during of farming years 1989-1990 though 2007-2008 had been analyzed, using nonparametric malmquist approach. so, amounts of inputs usages include seeds, fertilizers, dung, poison, herbicide, labor, water and acreage...

The d-glyceraldehyde 3-P dehydrogenases of spinach leaf, pea seed, and pea shoot were purified. The NADP and NAD-linked enzymes of either spinach leaves and pea shoots could not be separated. Changes in the ratio of NADP- to NAD-linked activity of the spinach leaf and pea shoot enzymes were observed during both purification and storage of crude extracts. The spinach leaf, pea shoot, and pea see...

BACKGROUND/AIMS Pulmonary endarterectomy (PEA) is the gold standard for treating chronic thromboembolic pulmonary hypertension (CTEPH) in Western countries. The aim of this study was to investigate the long-term outcomes of performing PEA on CTEPH patients in comparison with medical therapy at a single Korean center. METHODS This retrospective study included 88 CTEPH patients. These patients ...

In this study, the potential for a collection of wild-type L. lactis strains to metabolize breakdown products lignocellulose was investigated. The strains, isolated from variety environmental sources including grass and vegetables, were analyzed their ability ferment pentose sugars cellulolytic ability. total, 21 environment-derived evaluated. Eleven isolates found have commonly produced by bre...

Some growth parameters of pea (cv. Pleven 4) and vetch (cv. Obrazets 666) after treatment with organic fertilizer were studied in a field trial carried out at the Institute of Forage Crops, Pleven, Bulgaria. Humustim as organic fertilizer was applied through presowing treatment of seeds, treatment during vegetation and combination between both, at different doses. Ratios of aboveground weight t...

Fiory F, Formisano P, Perruolo G, Beguinot F. PED/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism. Am J Physiol Endocrinol Metab 297: E592–E601, 2009. First published June 16, 2009; doi:10.1152/ajpendo.00228.2009.—PED/ PEA-15 is a 15-kDa ubiquitously expressed protein implicated in a number of fundamental cellular functions, including apoptosis, proliferation,...

Phosphoprotein enriched in astrocytes-15 (PEA-15) is a cytoplasmic protein that sits at an important junction in intracellular signalling and can regulate diverse cellular processes, such as proliferation and apoptosis, dependent upon stimulation. Regulation of these processes occurs by virtue of the unique interaction of PEA-15 with other signalling proteins. PEA-15 acts as a cytoplasmic tethe...

BACKGROUND Pulmonary endarterectomy (PEA) is the treatment of choice in surgically accessible chronic thromboembolic pulmonary hypertension (CTEPH). An important predictor of outcome is postsurgical residual pulmonary hypertension. OBJECTIVE We aimed to use the hemodynamic response during exercise before PEA as a measurement for the hemodynamic outcome 1 year after PEA. METHODS Between Janu...

The effects of systemic administration of beta-phenylethylamine (beta-PEA) and microiontophoretically applied beta-PEA on the spontaneous discharge of dopamine (DA) neurons in the ventral tegmental area (VTA) of the anesthetized rat were examined. Intravenous administration of beta-PEA (1.0, 2.5, and 5.0 mg/kg) and microiontophoretic applications of beta-PEA caused inhibitory responses in DA ne...